Sitavio-M 50/850mg Tablet 60s (Box)

Sitavio-M 50/850mg Tablet is a combination oral antidiabetic medication belonging to the class of DPP-4 inhibitors and biguanides, containing two active ingredients — Sitagliptin (50mg) and Metformin Hydrochloride (850mg). If you are managing type 2 diabetes and your doctor has recommended this tablet, it is good to know that this medicine works through two complementary mechanisms to help regulate blood sugar levels in your body. Like most antidiabetic medicines, Sitavio-M may cause some side effects including nausea, diarrhoea, stomach upset, and in some cases mild upper respiratory tract infections — but many people tolerate it well when taken correctly. Before you start taking this tablet, always make sure you have a valid prescription from your doctor, and let your healthcare provider know about any other medicines or health conditions you currently have. Your health journey matters, and understanding what you are taking is the first step to staying safe and in control.

How to Take Sitavio-M 50/850mg Tablet

Sitavio-M 50/850mg Tablet should be taken orally with meals to help reduce the risk of gastrointestinal discomfort such as nausea or an upset stomach. Swallow the tablet whole with a glass of water — do not crush, chew, or split the tablet unless your doctor or pharmacist has specifically advised you to do so. Always follow your doctor's prescribed instructions carefully, as the timing and frequency of your dose may be adjusted based on your individual health condition and response to treatment.

Dosage of Sitavio-M 50/850mg Tablet

The commonly recommended dosage of Sitavio-M 50/850mg Tablet is typically one tablet taken twice daily with meals, though your doctor may adjust this based on your kidney function, blood sugar levels, and overall medical condition. Never self-adjust your dose — always follow the dosage instructions provided by your prescribing physician or pharmacist for safe and effective diabetes management.

Shelf Life of Sitavio-M 50/850mg Tablet

Sitavio-M 50/850mg Tablet generally has a shelf life of 24 to 36 months from the date of manufacture, as indicated on the product packaging. Always check the expiry date printed on the blister pack or carton before use, and do not consume the tablet if it has passed its expiry date. Using expired medication can reduce its effectiveness and may pose health risks.

How to Store Sitavio-M 50/850mg Tablet

• Store Sitavio-M 50/850mg Tablet at room temperature, below 30°C
• Keep the tablets in a cool, dry place away from direct sunlight, moisture, and heat
• Do not store in the bathroom or near kitchen sinks where humidity is high
• Keep the medicine out of reach of children and pets at all times
• Store the tablets in their original blister pack or container to protect them from environmental exposure
• If you notice any change in colour, texture, or smell of the tablet, do not use it and consult your pharmacist

Active Ingredient of Sitavio-M 50/850mg Tablet

Sitavio-M 50/850mg Tablet contains the following active pharmaceutical ingredients:

Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, while Metformin Hydrochloride is a biguanide-class antidiabetic agent. Together, they form a dual-action combination that addresses blood glucose regulation through two distinct pathways in the body.

Side Effects of Sitavio-M 50/850mg Tablet

As with all medicines, Sitavio-M 50/850mg Tablet may cause side effects in some individuals. Not everyone will experience them, but it is important to be aware of the following:

Common Side Effects:

• Nausea and vomiting
• Diarrhoea or loose stools
• Stomach pain or abdominal discomfort
• Loss of appetite
• Metallic taste in the mouth
• Headache
• Upper respiratory tract infection (e.g., runny nose, sore throat)
• Nasopharyngitis

Less Common Side Effects:

• Dizziness or lightheadedness
• Flatulence (excessive gas)
• Indigestion or heartburn
• Hypoglycaemia (low blood sugar), especially when combined with other antidiabetic medicines
• Skin rash or itching
• Urinary tract infection

Rare but Serious Side Effects (Seek Immediate Medical Attention):

• Lactic acidosis — symptoms include muscle pain, weakness, difficulty breathing, stomach discomfort, feeling cold, or dizziness (more associated with Metformin)
• Severe allergic reactions including swelling of the face, lips, tongue, or throat (angioedema)
• Severe and persistent joint pain (arthralgia)
• Pancreatitis — symptoms include severe and persistent abdominal pain that may radiate to the back
• Bullous pemphigoid (a rare skin blistering condition)

⚠️ If you experience any severe or unusual symptoms, stop taking the medication and contact your doctor or seek emergency medical care immediately.

Contraindications of Sitavio-M 50/850mg Tablet

• Hypersensitivity or allergy to Sitagliptin, Metformin, or any of the tablet's excipients
• Type 1 diabetes mellitus or diabetic ketoacidosis
• Severe renal impairment or kidney failure (eGFR below 30 mL/min/1.73m²)
• Hepatic impairment (liver disease or abnormal liver function)
• Lactic acidosis history — patients who have previously experienced lactic acidosis
• Acute or chronic conditions that may cause dehydration or tissue hypoxia, such as heart failure, respiratory failure, or recent myocardial infarction
• Excessive alcohol consumption on a regular basis
• Pregnancy and breastfeeding — unless specifically directed by a doctor
• Radiological contrast procedures — Metformin should be temporarily discontinued before iodinated contrast administration
• Paediatric use — not recommended for children unless prescribed by a specialist

Drug & Food Interaction of Sitavio-M 50/850mg Tablet

Drug Interactions:

• Insulin or other antidiabetic agents — concurrent use may increase the risk of hypoglycaemia (low blood sugar)
• Corticosteroids (e.g., prednisolone, dexamethasone) — may reduce the blood glucose-lowering effect of Sitavio-M
• Diuretics (e.g., furosemide, hydrochlorothiazide) — may affect kidney function and increase the risk of lactic acidosis
• ACE inhibitors (e.g., enalapril, lisinopril) — may increase the risk of hypoglycaemia
• Cimetidine — may increase Metformin plasma concentration by reducing renal clearance
• Iodinated contrast agents — Metformin should be stopped before and after procedures involving contrast dye
• Alcohol — increases the risk of lactic acidosis and hypoglycaemia; avoid excessive alcohol intake
• NSAIDs (e.g., ibuprofen, naproxen) — may affect kidney function, particularly in elderly patients
• Beta-blockers (e.g., propranolol) — may mask the symptoms of hypoglycaemia

Food Interactions:

• Alcohol — significantly increases the risk of lactic acidosis; limit or avoid alcohol while on this medication
• High-carbohydrate or sugary foods — may counteract the blood sugar-lowering effect of the medication
• Grapefruit or grapefruit juice — no significant known interaction, but consult your pharmacist if in doubt

Quick Tips for Sitavio-M 50/850mg Tablet

• Always take this tablet with food to minimise stomach-related side effects like nausea or diarrhoea
• Never skip or double your dose — if you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose
• Store your tablets properly — keep them in a cool, dry place away from heat, moisture, and direct sunlight
• Check the expiry date on the packaging before taking any tablet
• Keep a list of all your medications and share it with every doctor or pharmacist you visit to avoid harmful drug interactions
• Do not share your medication with others, even if they appear to have similar symptoms or conditions
• Inform your doctor immediately if you experience unusual muscle pain, difficulty breathing, stomach discomfort, or severe skin reactions
• Attend regular follow-up appointments and blood tests as advised by your doctor to monitor your kidney function and blood sugar levels
• Avoid excessive alcohol while taking this medication as it increases the risk of lactic acidosis
• Keep this medicine out of reach of children and store it in its original packaging at all times
• If you are scheduled for surgery or a scan involving contrast dye, inform your doctor that you are taking Metformin-containing medication, as it may need to be temporarily stopped

FAQs of Sitavio-M 50/850mg Tablet

Q1: Can I buy Sitavio-M 50/850mg Tablet online in Malaysia? 
Yes, you can purchase Sitavio-M 50/850mg Tablet through our licensed online pharmacy in Malaysia. We are committed to providing authentic, pharmacy-grade medicines with a safe and convenient ordering process — all from the comfort of your home.

Q2: Do I need a prescription to order Sitavio-M 50/850mg Tablet online in Malaysia? 
Yes, Sitavio-M 50/850mg Tablet is a prescription-only medicine (POM) in Malaysia. You will be required to submit a valid prescription from a registered medical practitioner before your order can be processed and dispatched. This is to ensure your safety and comply with Malaysian pharmaceutical regulations.

Q3: How do I submit my prescription when ordering online? 
It is simple and straightforward. You can upload a clear photo or scanned copy of your doctor's prescription during the checkout process on our website. Our licensed pharmacists will review and verify your prescription before approving your order.

Q4: Is the Sitavio-M 50/850mg Tablet sold on your website genuine and authentic?
 Absolutely. We only source our medicines from authorised distributors and licensed pharmaceutical suppliers in Malaysia. Every product listed on our platform, including Sitavio-M 50/850mg Tablet, is genuine, properly stored, and within its valid shelf life. Your safety is our top priority.

Q5: How long does delivery take for Sitavio-M 50/850mg Tablet within Malaysia? 
We offer delivery across Peninsular Malaysia and East Malaysia (Sabah and Sarawak). Standard delivery typically takes 2 to 5 working days, while express delivery options may be available depending on your location. You will receive a tracking number once your order has been dispatched.

Q6: Is my personal and medical information kept confidential when I order online? 
Yes, absolutely. We take your privacy very seriously. All personal details, prescription information, and order history are stored securely and handled in strict compliance with Malaysia's Personal Data Protection Act (PDPA). Your information will never be shared with third parties without your consent.

Q7: What should I do if my Sitavio-M 50/850mg Tablet arrives damaged or expired?
 If your order arrives damaged, tampered with, or past its expiry date, please contact our customer service team immediately with photos of the product and packaging. We will arrange for a replacement or refund in accordance with our returns and quality assurance policy.

Q8: Can I order Sitavio-M 50/850mg Tablet in bulk or for a longer supply period?
 Yes, you may order a larger supply based on your prescription coverage. However, the quantity dispensed will be subject to your doctor's prescription and our pharmacist's discretion to ensure responsible medicine dispensing practices.

Q9: How will my Sitavio-M 50/850mg Tablet be packaged for delivery?
 Your medication will be packed discreetly and securely to protect it during transit. We use appropriate packaging materials to ensure the tablets are not exposed to excessive heat or moisture during the delivery process.

Q10: What payment methods are accepted when ordering Sitavio-M 50/850mg Tablet online? 
We accept a variety of secure payment methods including online banking (FPX), credit and debit cards, and selected e-wallet options available in Malaysia. All transactions are processed through a secure payment gateway to protect your financial information.

Q11: Can I cancel or modify my order after it has been placed?
 Order cancellations or modifications may be possible if the order has not yet been processed or dispatched. Please contact our customer support team as soon as possible if you need to make any changes to your order.

Q12: How do I know if the online pharmacy I am ordering from is legitimate in Malaysia? 
A legitimate online pharmacy in Malaysia should be registered with the Ministry of Health (MOH) Malaysia and comply with all applicable pharmaceutical regulations. Look for clear contact information, a pharmacist verification process, and a requirement for valid prescriptions — all of which we proudly uphold on our platform.