Overview
Addison's Disease is also known as primary adrenocortical insufficiency. It happens when there is either destruction or dysfunction of the adrenal cortex leading to glucocorticoid (cortisol) and mineralocorticoid (aldosterone) deficiency.Signs and Symptoms
Pigmented skin, Weakness, Anorexia, Dizziness, Tiredness, Abdominal pain, Diarrhea, Constipation, Nausea and vomiting, Postural hypotension,Tachycardia, Hypoglycemia, VitiligoCommon Causes
Autoimmunity, Tuberculosis, Adrenal metastases, Lymphoma, Opportunistic infections such as HIV, Adrenal hemorrhageRisk Factors
Cancer, Taking blood thinning medication, Having opportunistic infections, Surgical removal of adrenal gland, Autoimmune diseaseInvestigation Techniques
Full blood count, Serum electrolytes, Serum glucose, ACTH stimulation testTreatment and Prevention
Hydrocortisone, Mineralocorticoids replacementPsychological Issues
Depression, Psychosis
