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Ankylosing Spondylitis


Ankylosing Spondylitis is a chronic inflammatory disease of the spine and sacroiliac joints of unknown etiology. It is more common in men than women. When it affects the spine, it causes the spine to be less flexible and results in hunching over time.

Signs and Symptoms

Low back pain worse at night, Stiffness of the back in the morning upon waking up, Pain radiates from sacroiliac joints to the buttocks and hips, Progressive loss of spinal movements

Common Causes

Unknown causes

Risk Factors

Age, Male gender, Genetic factors (HLA-B27 gene), Environmental factors

Investigation Techniques

Clinical examination of the spine and joints, MRI scan, X-ray of the affected joints, Full blood count

Treatment and Prevention

Physiotherapy, NSAIDs, TNF alpha-blockers, Local steroid injections, Surgery
Author Details
Information Updated on : Wed Feb 12 2020 08:04:04 GMT+0000 (Coordinated Universal Time)
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