OverviewAnkylosing Spondylitis is a chronic inflammatory disease of the spine and sacroiliac joints of unknown etiology. It is more common in men than women. When it affects the spine, it causes the spine to be less flexible and results in hunching over time.
Signs and SymptomsLow back pain worse at night, Stiffness of the back in the morning upon waking up, Pain radiates from sacroiliac joints to the buttocks and hips, Progressive loss of spinal movements
Common CausesUnknown causes
Risk FactorsAge, Male gender, Genetic factors (HLA-B27 gene), Environmental factors
Investigation TechniquesClinical examination of the spine and joints, MRI scan, X-ray of the affected joints, Full blood count
Treatment and PreventionPhysiotherapy, NSAIDs, TNF alpha-blockers, Local steroid injections, Surgery