Overview
Microscopic polyangiitis is a condition that is due to inflammation of the blood vessels which leads to multi-organ damages. However, the commonly affected organs are kidneys, lungs, skins, nerves and joints.Signs and Symptoms
Fever, Fatigue, Weight loss, Skin rash, Flu-like symptoms , Lungs- cough/ breathing problems/ spitting up blood , Gastrointestinal-bleeding in the gastrointestinal tract and abdominal pain , Brain/neurological-tingling/pain/weakness,/loss of sensation/ seizures , Musculoskeletal-joint pain/ muscle pain, HypertensionCommon Causes
Genetic factor predisposing to autoimmune reactionRisk Factors
Occupational , Environmental , Genetic , Autoimmune conditions.Investigation Techniques
Complete blood cell count, Erythrocyte sedimentation rate (ESR), Renal function test, Urine FEME, Antineutrophil cytoplasmic antibody (ANCA) test, Chest radiograph, Electrocardiography , Gastrointestinal endoscopy, Electromyography, Skin biopsyTreatment and Prevention
Remission induction using prednisone and cyclophosphamide, Maintenance of remission with Methotrexate and Prednisone, Intravenous immunoglobulin for refractory cases
