Overview
Raynaud's disease is a rare condition affecting the blood vessels commonly the fingers and toes. It causes the blood vessels to constrict and narrow during cold weather or under any form of stress.Signs and Symptoms
Cold fingers or toes , Color changes in your skin , Numbness, Prickly feeling , Stinging painCommon Causes
Connective tissue diseases (systemic sclerosis, scleroderma), Diseases of the blood vessels (Nitric oxide deficiency), Certain medications including beta blockers, Nerve processing dysfuctionRisk Factors
Female, Between the ages of 15 and 30, Cold climate, Family history, Associated diseases include conditions such as scleroderma and lupus, Certain occupations (vibration injury, PVC exposure).Investigation Techniques
Full blood count, Blood urea nitrogen, Creatinine, Prothrombin time Activated partial thromboplastin time, Serum glucose, Thyroid-stimulating hormone, Antinuclear antibody, Rheumatoid factor, Hepatitis panel Heavy metal screen, Serum protein and urine electrophoresisTreatment and Prevention
Alpha-1 blockers , Topical nitroglycerin ointment , Dihydropyridine calcium channel blockers , Other vasodilators (Losartan, Iloprost) , Sympathectomy , Chemical injectionPsychological Issues
Stress , Anxiety
