Overview
Wilson disease is a rare condition which is commonly due to genetic factor. It is an autosomal recessive type of inheritance which affects the copper metabolism where there will be excessive amount of copper in the body.Signs and Symptoms
Fatigue, Lack of appetite, Abdominal pain, Jaundice, Golden-brown eye discoloration (Kayser-Fleischer rings), Ascites & edema, Problems with speech or swallowing or physical coordination, Uncontrolled movements or muscle stiffnessCommon Causes
Genetic factorRisk Factors
Family history with same diseaseInvestigation Techniques
Liver function test, 24 Hour urine copper, Serum copper, Serum ceruloplasmin, Slit lamp examination, Liver biopsyTreatment and Prevention
Diet : Avoid foods with high copper content, Lifelong Penicillamine, Screen siblings, Liver transplantationPsychological Issues
Depression , Stress
