Casodex 50mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Casodex 50mg Tablet is a prescription-only medicine (POM) that contains Bicalutamide 50mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Casodex 50mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Casodex 50mg Tablet once daily at about the same time each day, with or without food, swallowing the tablet whole with water. Continue taking it exactly as prescribed by your specialist, and do not stop treatment abruptly even if you feel well, unless instructed to do so by your doctor.

Dosage

The dose and duration of Casodex 50mg Tablet will be individualised and closely monitored by your treating doctor as part of your overall prostate cancer treatment plan, commonly one tablet once daily alongside an LHRH analogue. Never change your dose or stop this medicine without first discussing it with your specialist, and attend all scheduled monitoring appointments and blood tests.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Hot flashes
  • Breast tenderness or enlargement
  • Diarrhea
  • Nausea
  • Fatigue
  • Rash
  • Dizziness
  • Liver function changes

Contraindications

  • Known hypersensitivity to bicalutamide or any ingredient in this product
  • Use in women (this medicine is indicated for men with prostate cancer only)
  • Severe hepatic impairment (requires specialist assessment)
  • Concomitant use with terfenadine, astemizole, or cisapride

Drug / Food Interactions

  • Warfarin and other anticoagulants may have an enhanced blood-thinning effect, requiring closer INR monitoring by your doctor
  • Bicalutamide can inhibit CYP3A4 and may increase blood levels of certain other medicines metabolised by this enzyme, including midazolam-type sedatives
  • Other medicines affecting liver enzyme function may alter bicalutamide levels and should be reviewed by your specialist

Quick Tips

  • Attend all scheduled specialist appointments and blood tests for liver function monitoring
  • Contact your doctor immediately if you notice yellowing of the skin/eyes, dark urine, or unusual tiredness
  • Do not stop or adjust this medicine without your specialist’s advice, even during an LHRH analogue course
  • Tell every doctor and pharmacist you see that you are taking this medicine, especially before starting anything new

Ingredients / Active Ingredients

  • Bicalutamide 50mg

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Safe

This medicine is not safe during breastfeeding and should be avoided.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Frequently Asked Questions

Product Specifications

BrandAstraZeneca
ClassificationPrescription medicine
Ingredients / Active IngredientsBicalutamide
Pack Size28s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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