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Glucophage 1000mg Tablet 15s (strip) - DoctorOnCall Online Pharmacy
Glucophage 1000mg Tablet 15s (strip) - DoctorOnCall Online Pharmacy
Glucophage 1000mg Tablet 15s (strip) - DoctorOnCall Online Pharmacy Glucophage 1000mg Tablet 15s (strip) - DoctorOnCall Online Pharmacy

Glucophage 1000mg Tablet 15s (strip)

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Glucophage 1000mg Tablet 15s (strip) - DoctorOnCall Online Pharmacy

Glucophage 1000mg Tablet 15s (strip)

RM 20.10

Product Overview

Introduction of Glucophage 1000mg Tablet 15s (strip)

Glucophage 1000mg Tablet is a well-known and widely trusted prescription medicine that belongs to the biguanide drug class, with Metformin Hydrochloride 1000mg as its active ingredient — one of the most extensively studied and globally prescribed oral pharmaceutical compounds available today. As with all medicines, there are side effects you should be aware of before starting treatment, and the most commonly reported ones include nausea, vomiting, diarrhoea, and abdominal discomfort — particularly during the early stages of therapy — which is why this tablet is typically taken with or immediately after a meal. You should also know that while rare, a serious condition called lactic acidosis (a dangerous build-up of lactic acid in the blood) has been associated with Metformin use, and if you experience symptoms such as muscle pain, difficulty breathing, stomach pain, or unusual tiredness, you should seek immediate medical attention. Glucophage is a brand-name product manufactured by Merck KGaA — a globally respected, science-led pharmaceutical company with over 350 years of heritage — which means when you purchase Glucophage 1000mg, you are receiving an originator brand product held to the highest international manufacturing standards. This tablet requires a valid prescription, and it is important that you share your full medical history with your doctor, especially regarding kidney function, liver health, and any planned surgical procedures, before starting or continuing this medication.

How to Take Glucophage 1000mg Tablet

Glucophage 1000mg Tablet should be swallowed whole with a glass of water and taken with or immediately after a meal — this is important, as taking it with food significantly reduces the likelihood of gastrointestinal side effects such as nausea and stomach upset. Do not crush, chew, or split the tablet unless specifically advised by your doctor, as this may alter the rate of drug release. Always follow the exact dosage schedule prescribed by your doctor, take it at the same time each day to maintain consistent drug levels, and never adjust your dose or stop taking it without medical guidance.

Dosage of Glucophage 1000mg Tablet

The standard recommended dose of Glucophage 1000mg Tablet is one tablet (1000mg of Metformin Hydrochloride) taken orally twice daily, typically with morning and evening meals — though your doctor may start you on a lower dose and gradually increase it to minimise gastrointestinal side effects. The maximum daily dose of Metformin in adults is generally 3000mg, and all dosage decisions — including initiation, titration, and duration — must be made and supervised by a qualified and registered medical practitioner based on your individual clinical profile and kidney function.

Shelf Life of Glucophage 1000mg Tablet

Glucophage 1000mg Tablet typically carries a shelf life of 36 months (3 years) from the date of manufacture, as printed on the blister pack and outer carton. Always check the expiry date before consuming any tablet — do not use this medicine beyond its stated expiry date even if the tablets appear physically intact, as the stability and potency of Metformin Hydrochloride cannot be guaranteed once the expiry has passed. Dispose of any expired or unused tablets responsibly by returning them to a licensed pharmacy for proper pharmaceutical waste disposal — do not discard in regular household waste or flush down a drain, as Metformin is a compound that has been identified in environmental water sources and responsible disposal matters.

How to Store Glucophage 1000mg Tablet

Store Glucophage 1000mg Tablet at room temperature, below 25°C, in a cool, dry, and well-ventilated place away from direct sunlight, heat, and humidity. Malaysia's tropical climate means you should be especially careful to avoid storing this medication in the bathroom, near the kitchen sink, on windowsills, or inside a vehicle, as persistent heat and moisture can compromise tablet integrity and reduce the effectiveness of the active ingredient over time. Keep the tablets in their original blister packaging with the outer carton intact until the point of use, as the packaging provides essential protection from environmental degradation. Store completely out of reach of children at all times, and do not transfer tablets to unlabelled containers, as this increases the risk of medication errors.

Active Ingredient of Glucophage 1000mg Tablet

The active pharmaceutical ingredient (API) in Glucophage 1000mg Tablet is Metformin Hydrochloride 1000mg. Metformin is a dimethylbiguanide compound and is one of the most extensively studied oral pharmaceutical agents in modern medicine, with over six decades of documented clinical use worldwide. It is listed on the World Health Organization's (WHO) Model List of Essential Medicines and is widely recognised in international clinical guidelines as a first-line oral pharmacological agent for the management of type 2 diabetes mellitus in adults. Metformin Hydrochloride exerts its primary pharmacological action by reducing hepatic glucose production (gluconeogenesis), improving peripheral insulin sensitivity in muscle and adipose tissue, and reducing intestinal glucose absorption — making it a multi-mechanistic agent with a well-characterised pharmacokinetic and pharmacodynamic profile. Glucophage 1000mg tablets are film-coated and contain approved pharmaceutical excipients including povidone, magnesium stearate, and a hypromellose-based film coating — all selected for their role in tablet cohesion, stability, and patient acceptability. As an originator brand product manufactured by Merck KGaA under stringent Good Manufacturing Practice (GMP) standards, Glucophage represents the benchmark reference formulation against which all generic Metformin products are assessed for bioequivalence.

Side Effects of Glucophage 1000mg Tablet

Glucophage 1000mg Tablet may cause side effects in some individuals. Many gastrointestinal effects are dose-dependent and tend to improve as the body adjusts to the medication, particularly when the tablet is taken with food. Being aware of both common and less common reactions helps you use this medicine safely and responsibly.

Very Common and Common Side Effects (Gastrointestinal):

  • Nausea — a frequently reported effect, particularly at the start of treatment or following a dose increase
  • Vomiting
  • Diarrhoea — often transient; taking the tablet with food significantly reduces this risk
  • Abdominal pain or stomach cramps
  • Loss of appetite (anorexia)
  • Metallic taste in the mouth (dysgeusia) — a well-documented and generally harmless early side effect
  • Flatulence and bloating

Less Common Side Effects:

  • Vitamin B12 deficiency (cyanocobalamin) — long-term Metformin use is associated with reduced Vitamin B12 absorption; your doctor may recommend periodic monitoring of B12 levels, particularly if you experience symptoms of peripheral neuropathy (tingling, numbness in hands or feet), fatigue, or anaemia
  • Skin reactions — including erythema (skin reddening), pruritus (itching), or urticaria (hives) in rare cases of hypersensitivity
  • Hepatitis (liver inflammation) — very rare; if you notice yellowing of the skin or eyes (jaundice), dark urine, or upper right abdominal pain, seek medical attention promptly

Rare but Serious: Lactic Acidosis

  • Lactic acidosis — a rare but potentially life-threatening metabolic complication characterised by an abnormal accumulation of lactic acid in the blood. Symptoms include severe muscle pain or weakness, difficulty breathing, stomach pain, nausea, vomiting, dizziness, feeling cold, or an irregular heartbeat. Risk is significantly elevated in patients with renal impairment, hepatic dysfunction, cardiac failure, dehydration, excessive alcohol consumption, or those undergoing procedures requiring iodinated contrast media. If you experience any of these symptoms, stop taking Glucophage immediately and seek emergency medical care.

Important: This is not a complete list of all possible side effects. Always report any new or worsening symptoms to your doctor or pharmacist, and do not discontinue Glucophage without medical guidance.

Contraindications of Glucophage 1000mg Tablet

  • Renal impairment or kidney dysfunction — Glucophage is contraindicated in patients with an estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73m²...
  • Acute or chronic conditions associated with tissue hypoxia...
  • Hepatic impairment or significant liver disease...
  • Known hypersensitivity to Metformin Hydrochloride...
  • Diabetic ketoacidosis (DKA) or pre-coma...
  • Iodinated contrast media procedures...
  • Acute alcohol intoxication and chronic alcoholism...
  • Breastfeeding...
  • Children under 10 years of age...

Drug & Food Interactions of Glucophage 1000mg Tablet

Drug Interactions:

  • Iodinated contrast agents (radiographic dye)
  • Alcohol and alcohol-containing medications
  • Other antidiabetic agents
  • Carbonic anhydrase inhibitors
  • Cationic drugs competing for renal tubular secretion
  • Corticosteroids
  • Diuretics
  • Beta-2 agonists
  • ACE inhibitors and angiotensin receptor blockers (ARBs)
  • Nifedipine (calcium channel blocker)

Food Interactions:

  • Glucophage 1000mg Tablet should always be taken with food or immediately after a meal
  • Alcohol (including beer, wine, and spirits)
  • High-carbohydrate or high-sugar meals
  • Caffeine
  • Vitamin B12 absorption

Quick Tips for Glucophage 1000mg Tablet

  • Always have a valid prescription
  • Buy from a licensed pharmacy only
  • Inspect your order on delivery
  • Always take with food
  • Take at the same time each day
  • Never skip kidney function tests
  • Inform your doctor before any surgical procedure or imaging scan
  • Limit alcohol consumption
  • Monitor for signs of Vitamin B12 deficiency
  • Do not stop taking Glucophage without medical advice
  • Store below 25°C in original packaging
  • Keep out of reach of children at all times
  • Dispose of expired or unused tablets responsibly

FAQs — Glucophage 1000mg Tablet

Can I buy Glucophage 1000mg Tablet online in Malaysia?

Yes, Glucophage 1000mg Tablet is available for purchase through our licensed online pharmacy in Malaysia. We are fully authorised to dispense prescription medicines in compliance with Malaysian pharmaceutical regulations and under the oversight of registered pharmacists. A valid prescription from a licensed medical practitioner is required and must be submitted before your order can be verified, approved, and dispatched.

Is a prescription required to purchase Glucophage 1000mg in Malaysia?

Yes, without exception. Glucophage 1000mg Tablet (Metformin Hydrochloride 1000mg) is a prescription-only medicine (POM) under Malaysian pharmaceutical law. Our dispensing pharmacists will review and verify your prescription document before any order is processed. We do not dispense this medication without a valid prescription — this is both a legal requirement and a critical patient safety measure, as Metformin carries specific contraindications related to kidney function and other medical conditions that must be assessed by a qualified doctor.

Is Glucophage 1000mg Tablet readily available and can it be delivered nationwide across Malaysia?

Yes, Glucophage 1000mg Tablet is a core part of our pharmacy inventory and is available for delivery to addresses throughout Peninsular Malaysia, Sabah, and Sarawak. Standard delivery typically takes 3 to 5 working days, with express delivery options available for selected locations. Once your prescription is verified and your order confirmed, you will receive a shipment tracking number so you can monitor your delivery in real time.

How do I know the Glucophage 1000mg I receive is genuine and not a counterfeit?

Authenticity is something we take very seriously. All products supplied through our online pharmacy are sourced exclusively from authorised pharmaceutical distributors and verified supply chains. Glucophage is a brand-name originator product manufactured by Merck KGaA — when your order arrives, check for the Glucophage brand name and Merck KGaA markings on the packaging, intact blister seals, a clearly printed batch number, manufacture date, and expiry date. You may also verify the product's registration status with the National Pharmaceutical Regulatory Agency (NPRA) Malaysia through their official online product search portal. If anything appears unusual, do not consume the product and contact our team immediately.

What is the price of Glucophage 1000mg Tablet in Malaysia?

The price of Glucophage 1000mg Tablet varies depending on the pack size and any applicable dispensing fees. As a branded originator product, it is priced accordingly and reflects the Merck KGaA quality standard. We maintain transparent and competitive pricing with no hidden charges. For the most current and accurate pricing, please refer to the product listing page on our website. If you are on a regular long-term prescription and would like to discuss volume or repeat-order options, our pharmacist team is available to assist.

How will my Glucophage 1000mg order be packaged for delivery?

All orders are packed in discreet, tamper-evident outer packaging with no indication of the product contents — your privacy is fully protected. We ensure that tablets are adequately cushioned and protected from moisture and heat during transit, which is particularly important given Malaysia's warm and humid climate. You will receive your order in the manufacturer's original sealed blister packaging inside a secure outer parcel.

How should I store Glucophage 1000mg Tablet once it arrives?

Once received, store Glucophage 1000mg Tablet at room temperature below 25°C, in a cool and dry location away from direct sunlight, heat, and humidity. Avoid bathroom cabinets, kitchen windowsills, and vehicle storage — all areas prone to temperature fluctuation in Malaysia's climate. Keep tablets in their original blister packaging with the outer carton intact, and store completely out of reach of children at all times.

What should I do if I receive the wrong product or a damaged pack of Glucophage 1000mg?

If you receive a damaged, incorrect, or tampered product, please contact our customer service team within 48 hours of delivery, along with clear photographs of the issue. We will arrange a replacement or appropriate resolution in accordance with our returns and pharmaceutical handling policy. Please note that correctly dispensed prescription medicines cannot be returned for change-of-mind reasons under applicable pharmacy regulations — this is a standard regulatory requirement for patient safety and product integrity.

Is it safe to purchase Glucophage 1000mg from an online pharmacy in Malaysia?

Yes — when ordered from a properly licensed, MOH-compliant online pharmacy, it is safe and convenient. Our pharmacy is fully registered, operates under the regulatory framework of the Ministry of Health Malaysia and the Pharmacy Board Malaysia, employs qualified registered pharmacists, and sources all products from NPRA-registered distributors. We strongly advise against purchasing Glucophage or any prescription medicine from unlicensed online platforms, social media sellers, or unverified marketplaces, as these carry a significant risk of receiving counterfeit, substandard, expired, or improperly stored medications.

How do I submit my prescription when ordering Glucophage 1000mg online?

During the checkout process on our website, you will be prompted to upload a clear photograph or scanned copy of your valid prescription. Our registered dispensing pharmacist will review the document to confirm it meets all required criteria — including the prescribing doctor's registration, legibility, medication details, and validity — before approving your order for dispatch. If you need assistance with the upload process, our customer support team is available via live chat, email, or telephone to guide you.

Is Glucophage 1000mg the same as generic Metformin 1000mg tablets available in Malaysia?

Glucophage 1000mg is the originator brand-name product containing Metformin Hydrochloride 1000mg, manufactured by Merck KGaA. Generic Metformin 1000mg tablets — produced by other NPRA-registered pharmaceutical manufacturers — contain the same active ingredient at the same dose and are required to demonstrate bioequivalence to the reference product. While both contain Metformin Hydrochloride 1000mg as the active ingredient, there may be differences in excipients, tablet coating, and manufacturing processes. If you have been specifically prescribed Glucophage by brand name, or have a preference for the originator product, our pharmacy can supply it accordingly. Consult your doctor or pharmacist if you have questions about interchangeability.

What should I do if I accidentally miss a dose of Glucophage 1000mg?

If you miss a dose of Glucophage 1000mg and remember it within the same mealtime, take it as soon as possible with food. However, if it is already close to the time of your next scheduled dose, skip the missed tablet entirely and continue with your regular twice-daily schedule. Never take two doses at the same time or double your dose to compensate for a missed one — this does not improve outcomes and may increase the risk of side effects. If you are unsure, consult your doctor or pharmacist for personalised guidance.

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Brands

Merck

Active Ingredient

metformin 

Manufactured by

Merck Healthcare

Side Effects

As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.

Cough or hoarseness, Decreased appetite, Diarrhea, Dyspnea, Upper respiratory tract infection, Nausea, Vomiting, Flatulence, Heartburn/dyspepsia, Abdominal distention, Constipation.

Warning Precautions

Alcohol Warning (Not Advisable)

It is unsafe to consume alcohol with Glucophage 1000mg Tablet 15s (strip). Alcohol intoxication can increase the risk of lactic acidosis particularly in case of fasting, malnutrition or hepatic impairment.

Pregnancy Warning (Maybe Safe)

Glucophage 1000mg Tablet 15s (strip) should be safe to use during pregnancy because either animal or human studies have not shown any adverse effects on the fetus, however, uncontrolled hyperglycemia in people with PCOS can increase the risk of congenital abnormalities and intrauterine death.

Breastfeeding Warning (Limited Data)

Limited human studies suggest that Glucophage 1000mg Tablet 15s (strip) does not represent a significant risk to the baby when used during pregnancy. In regards to limited data, please consult your doctor to decide on discontinuation of breastfeeding or Glucophage 1000mg Tablet 15s (strip).

Driving Warning (Generally Safe)

Glucophage 1000mg Tablet 15s (strip) usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Warning (High Risk)

Glucophage 1000mg Tablet 15s (strip) is not recommended in patients with severe kidney disease, especially in patients with creatinine clearance less than 60mL/min. Patients with severe kidney disease has high risk to get lactic acidosis. Dose adjustment of Glucophage 1000mg Tablet 15s (strip) and regular check up to monitor renal function may be needed. Please consult your doctor before consumption.

Liver Warning (Limited Data)

Glucophage 1000mg Tablet 15s (strip) should be used with caution in patients with liver disease due to increased risk of lactic acidosis. Hence liver function test should be done before initiating Glucophage 1000mg Tablet 15s (strip). Discontinuation of Glucophage 1000mg Tablet 15s (strip) may be needed if there is deterioration of liver function. Please consult your doctor.

Quick Tips

  • Do not disregard any feeling of deep or fast breathing, prolonged nausea, or vomiting, since these symptoms may be indications of lactic acidosis, a potentially fatal disease called lactic acidosis.
  • Using Glucophage 1000mg Tablet regularly may lead to vitamin B12 insufficiency, resulting in anaemia, tiredness, pale skin, shortness of breath, or headache. If you see any of these symptoms, notify your doctor immediately.
  • Regular blood sugar and renal monitoring will be recommended while you are on Glucophage 1000mg Tablet.

FAQ

Disclaimer

Information last updated on: Fri Apr 03 2026 15:07:30 GMT+0000 (Coordinated Universal Time) The product images shown are for illustration purposes only and may not be an exact representation of the product.

The content provided on this webpage is to provide information only, to be fully-interpreted by a medical professional, and not intended as a guide to make purchase decisions, or a substitute to advice of a medical professional. Effectiveness and side effects of medication may differ from individual to individual. We do not encourage any customer to self-diagnose and/or self-medicate. Patients should always consult a medical professional before taking or using any medication. The content provided here is non-exhaustive and may not cover all aspects of the medication. Our service should only be used to support the doctor-patient dynamic, not replace it.

The fulfilment of prescription medication is subject to our review of a prescription issued by a Malaysian Medical Council (MMC) registered doctor. If required, we will provide a tele-consult service with one of our registered panel doctors. This is not an advertisement of a medicine as such an advertisement would require prior approval from the Medicines Advertisement Board of Malaysia. Glucophage 1000mg Tablet 15s (strip) is available in many areas in Malaysia. Kuala Lumpur, Bukit Bintang, Titiwangsa, Setiawangsa, Wangsa Maju, Kepong, Segambut, Bandar Tun Razak, Cheras, Subang Jaya, Petaling Jaya, Mont Kiara, Puchong, Bandar Sunway, TTDI, Seri Kembangan, Klang, Bukit Tinggi, Damansara, Sentul, Penang, George Town, Jelutong, Gelugor, Bayan Baru, Bandar Baru Air Itam, Sungai Ara, Bukit Mertajam, Butterworth, Perai, Johor Bahru, Skudai, Bukit Indah, Gelang Patah, Senai, Pasir Gudang, Taman Daya, Taman Molek, Taman Perling, Tebrau, Danga Bay, Larkin, Nusajaya, Pontian, Masai, Setia Tropika, Desaru, Tampoi.


Glucophage 1000mg Tablet 15s (strip) is available at many places in Singapore. Ang Mo Kio, Alexandra, Admiralty, Bedok, Bishan, Bukit Batok, Bukit Merah, Bukit Panjang, Bukit Timah, Boat Quay, Buona Vista, Beach Road, Bugis, Balestier, Boon Lay, Central Area, Choa Chu Kang, Clementi, Chinatown, Commonwealt, City Hall, Clarke Quay, Changi Airport, Changi Village, Clementi Park, Dairy Farm, Eunos, East Coast, Farrer Park, Geylang, Hougang, Harbourfront, Holland, Jurong, Jurong East, Jurong West, Kallang/ Whampoa, Lim Chu Kang, Marine Parade, Marina, Macpherson, Mandai, Newton, Novena, Orchard, Pasir Ris, Punggol, Potong Pasir, Paya Lebar, Queenstown, Raffles Place, Rochor, River Valley, Sembawang, Sengkang, Serangoon, Serangoon Rd, Seletar, Tampines, Toa Payoh, Tanjong Pagar, Telok Blangah, Tanglin, Thomson, Tuas, Tengah, Upper East Coast, Upper Bukit Timah, Upper Thomson, Woodlands, West Coast, Yishun, Yio Chu Kang.
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