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Janumet XR 100/1000mg Tablet 28s - DoctorOnCall Online Pharmacy
Janumet XR 100/1000mg Tablet 28s - DoctorOnCall Online Pharmacy
Janumet XR 100/1000mg Tablet 28s - DoctorOnCall Online Pharmacy Janumet XR 100/1000mg Tablet 28s - DoctorOnCall Online Pharmacy

Janumet XR 100/1000mg Tablet 28s

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Prescription Required
This medication requires a valid prescription from a doctor.
Don’t Have A Prescription? Get A Consult With Our Doctor Today.
STEP 1
Checkout & review your order.
STEP 2
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STEP 3
Our doctor will contact you within 1-hour of your purchase.
Term & Condition
100% Authentic
We ensure that all our pharmaceutical products including health supplements and traditional preparations are registered with the National Pharmaceutical Regulatory Authority (NPRA) Malaysia
Free Delivery on orders above RM120
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Daily Operational Hours for consultations:
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CLOSE
Prescription Required
This medication requires a valid prescription from a doctor.
Don’t Have A Prescription? Get A Consult With Our Doctor Today.
STEP 1
Checkout & review your order.
STEP 2
Make payment.
STEP 3
Our doctor will contact you within 1-hour of your purchase.
Term & Condition
100% Authentic
We ensure that all our pharmaceutical products including health supplements and traditional preparations are registered with the National Pharmaceutical Regulatory Authority (NPRA) Malaysia
Free Delivery on orders above RM120
Enjoy free delivery with a minimum spend of RM120 on our platform.

Product Overview

Introduction of Janumet XR 100/1000mg Tablet 28s

Janumet XR 100/1000mg Tablet is a combination prescription medicine that belongs to the class of antidiabetic agents, specifically combining a DPP-4 inhibitor with a biguanide. It contains two active ingredients — Sitagliptin and Metformin Hydrochloride — working together in a single extended-release tablet. If you are taking this medicine, there are a few things worth knowing: like most medications, it can cause some side effects such as nausea, diarrhoea, stomach upset, and in rare cases, a serious condition called lactic acidosis. You should also be aware that this is a prescription-only medicine, so it is important to take it exactly as your doctor has advised and never adjust your dose on your own. We want you to feel confident and informed every step of the way, because your health and safety truly matter to us.

How to Take Janumet XR 100/1000mg Tablet

Janumet XR 100/1000mg Tablet should be taken orally with food, preferably with your evening meal, to help reduce the chance of stomach-related discomfort. Swallow the tablet whole — do not crush, cut, or chew it, as this is an extended-release formulation designed to release the medicine gradually into your body. Always follow your doctor's or pharmacist's specific instructions regarding timing and frequency, as individual requirements may vary.

Dosage of Janumet XR 100/1000mg Tablet

The typical recommended dose of Janumet XR 100/1000mg is one tablet taken once daily with the evening meal, though your doctor may adjust the dosage based on your individual medical condition, kidney function, and response to treatment. Never self-adjust your dose — always follow the prescription provided by your healthcare provider.

Shelf Life of Janumet XR 100/1000mg Tablet

Janumet XR 100/1000mg Tablet generally has a shelf life of up to 3 years from the date of manufacture, as indicated on the packaging. Always check the expiry date printed on the box or blister pack before use, and do not take the tablet if it has passed its expiration date. Expired medication should be disposed of safely and responsibly — your pharmacist can guide you on proper disposal methods.

How to Store Janumet XR 100/1000mg Tablet

Store Janumet XR 100/1000mg Tablet at room temperature, below 25°C, in a cool and dry place away from direct sunlight, heat, and moisture. Keep the tablets in their original packaging and ensure the container is tightly closed after each use. As with all medications, store this product out of reach of children and pets to prevent accidental ingestion.

Active Ingredient of Janumet XR 100/1000mg Tablet

Janumet XR 100/1000mg Tablet contains the following active pharmaceutical ingredients:

Sitagliptin — 100mg (as Sitagliptin Phosphate Monohydrate)

Metformin Hydrochloride — 1000mg (extended-release formulation)

These two active ingredients are combined in a single tablet to provide a dual-action formulation in an extended-release form.

Side Effects of Janumet XR 100/1000mg Tablet

Like all medicines, Janumet XR 100/1000mg Tablet may cause side effects in some people. Not everyone will experience them, but it is important to be aware of the following:

Common Side Effects:

  • Nausea and vomiting
  • Diarrhoea or loose stools
  • Stomach pain or abdominal discomfort
  • Decreased appetite
  • Headache
  • Upper respiratory tract infection (e.g., runny nose, sore throat)
  • Nasopharyngitis

Less Common Side Effects:

  • Hypoglycaemia (low blood sugar), especially when combined with other antidiabetic medicines
  • Dizziness
  • Constipation
  • Flatulence (gas)
  • Urinary tract infection
  • Skin rash or itching

Serious but Rare Side Effects (Seek Immediate Medical Attention):

  • Lactic acidosis — a rare but serious condition associated with Metformin; symptoms include muscle pain, difficulty breathing, stomach discomfort, feeling cold, or unusual weakness
  • Pancreatitis — severe and persistent abdominal pain that may radiate to the back
  • Severe allergic reactions — including swelling of the face, lips, tongue or throat, difficulty breathing, or skin blistering
  • Severe joint pain (arthralgia) — has been reported with DPP-4 inhibitors including Sitagliptin
  • Bullous pemphigoid — a type of skin blistering reaction

⚠️ If you experience any serious or unusual symptoms, stop taking the medication and consult your doctor or seek emergency medical care immediately.

Contraindications of Janumet XR 100/1000mg Tablet

  • You have a known allergy or hypersensitivity to Sitagliptin, Metformin, or any other ingredient in the tablet
  • You have severe renal impairment (kidney disease) or are on dialysis
  • You have diabetic ketoacidosis or diabetic pre-coma
  • You have acute or chronic metabolic acidosis, including lactic acidosis
  • You are suffering from severe hepatic impairment (liver disease)
  • You are experiencing acute conditions that may affect kidney function, such as dehydration, severe infection, shock, or recent administration of iodinated contrast agents
  • You have a history of heart failure or conditions associated with hypoxaemia (low oxygen levels in the blood)
  • You are pregnant or breastfeeding — consult your doctor before taking this medicine
  • You are under 18 years of age — safety and efficacy have not been established in paediatric patients

📌 Always inform your doctor about all existing medical conditions and current medications before starting Janumet XR.

Drug & Food Interaction of Janumet XR 100/1000mg Tablet

Drug Interactions:

  • Insulin or other antidiabetic medicines — may increase the risk of hypoglycaemia
  • Diuretics (water tablets) such as furosemide — may affect kidney function and Metformin levels
  • Corticosteroids (e.g., prednisolone) — may raise blood sugar levels and reduce the effectiveness of this medicine
  • Beta-blockers (e.g., propranolol) — may mask the symptoms of low blood sugar
  • ACE inhibitors (e.g., enalapril) — may increase the risk of lactic acidosis
  • Iodinated contrast media — Metformin should be temporarily discontinued before and after procedures involving iodinated contrast dye due to the risk of acute kidney injury and lactic acidosis
  • Cimetidine and other cationic drugs — may increase plasma Metformin concentration
  • Alcohol — excessive alcohol intake increases the risk of lactic acidosis with Metformin

Food Interactions:

  • Take Janumet XR with food (preferably the evening meal) to reduce gastrointestinal side effects
  • Avoid excessive alcohol consumption while on this medication, as it can affect blood sugar levels and increase the risk of lactic acidosis
  • High-carbohydrate or sugary meals should be managed carefully as part of your overall diabetes management plan

💊 Always tell your doctor and pharmacist about all prescription medicines, over-the-counter drugs, supplements, and herbal products you are currently taking.

Quick Tips for Janumet XR 100/1000mg Tablet

  • Always take Janumet XR with your evening meal — this helps reduce nausea and stomach discomfort
  • Swallow the tablet whole — never crush, split, or chew it as it is an extended-release formulation
  • Do not skip doses — take it at the same time each day to maintain consistent blood levels
  • Store in a cool, dry place below 25°C — keep away from direct sunlight, heat, and humidity
  • Keep out of reach of children — store in a secure location at all times
  • Check the expiry date before taking any tablet — never use expired medication
  • Do not share your medication with others, even if they have similar symptoms or conditions
  • Inform your doctor before any surgery or medical procedure — Metformin may need to be temporarily stopped
  • Avoid excessive alcohol while on this medication to reduce the risk of lactic acidosis
  • Keep all follow-up appointments with your doctor for regular monitoring of kidney function and blood sugar levels
  • Purchase only from licensed and verified pharmacies — ensure your medication is authentic and properly stored before it reaches you

Frequently Asked Questions (FAQs) about Janumet XR 100/1000mg Tablet

Q1: Can I buy Janumet XR 100/1000mg Tablet online in Malaysia?
Yes, you can purchase Janumet XR 100/1000mg Tablet through our licensed online pharmacy in Malaysia. We are a registered pharmacy that complies with Malaysian pharmaceutical regulations, ensuring that every product sold is authentic, properly sourced, and safely delivered to your doorstep.

Q2: Do I need a prescription to order Janumet XR 100/1000mg Tablet in Malaysia?
Yes, Janumet XR 100/1000mg is a prescription-only medicine (POM) in Malaysia. You will be required to provide a valid prescription from a registered medical practitioner before your order can be processed. This is to ensure your safety and that the medication is appropriate for your specific health condition.

Q3: How do I submit my prescription when ordering online?
You can upload a clear photo or scanned copy of your valid prescription during the checkout process on our website. Our licensed pharmacist will review and verify your prescription before your order is confirmed and dispatched. If you have any questions about the prescription submission process, our customer support team is happy to assist you.

Q4: Is the Janumet XR 100/1000mg Tablet sold on your website genuine and authentic?
Absolutely. We source all our medications directly from authorised distributors and pharmaceutical suppliers registered with the Ministry of Health Malaysia (MOH). Every product on our platform is verified for authenticity, proper storage, and quality assurance before it is made available for purchase.

Q5: How long does delivery take for Janumet XR 100/1000mg Tablet within Malaysia?
We offer reliable delivery across Peninsular Malaysia, Sabah, and Sarawak. Standard delivery typically takes 2 to 5 working days, while express delivery options may be available depending on your location. You will receive a tracking number once your order has been dispatched so you can monitor your delivery in real time.

Q6: Is it safe to order prescription medicine online in Malaysia?
Yes, it is safe — provided you order from a licensed and regulated online pharmacy like ours. We operate in full compliance with Malaysian pharmacy laws and regulations. Our team of registered pharmacists oversees every order to ensure that medicines are dispensed responsibly and safely.

Q7: What should I do if my Janumet XR tablets arrive damaged or appear tampered with?
If your order arrives damaged, tampered with, or if the packaging looks suspicious, do not consume the medication. Contact our customer service team immediately with photos of the product and packaging. We will arrange for a replacement or refund in accordance with our returns and quality assurance policy.

Q8: Can I get a refill of Janumet XR 100/1000mg through your online pharmacy?
Yes, refills are available through our platform. However, each refill will require a valid and current prescription. We recommend planning your refill in advance to avoid any gaps in your medication supply. You may also contact our pharmacist team for guidance on managing your prescription refills.

Q9: How is Janumet XR 100/1000mg packaged for delivery to ensure its quality?
We take product integrity very seriously. All medications are packaged in secure, tamper-evident packaging and dispatched under appropriate storage conditions to maintain product quality during transit. Temperature-sensitive medicines are handled with additional care to ensure they reach you in optimal condition.

Q10: What payment methods are accepted when ordering Janumet XR 100/1000mg online in Malaysia?
We accept a variety of secure payment methods including online banking (FPX), credit and debit cards, and selected e-wallets commonly used in Malaysia. All transactions are processed through a secure payment gateway to protect your personal and financial information.

Q11: Can I cancel or modify my order after it has been placed?
Order cancellations or modifications may be possible if your order has not yet been processed or dispatched. Please contact our customer service team as soon as possible if you need to make any changes. Once an order has been confirmed and dispatched, cancellations may not be possible due to the nature of prescription medications.

Q12: How do I know if the online pharmacy I am ordering from is legitimate in Malaysia?
A legitimate online pharmacy in Malaysia should be registered with the Ministry of Health (MOH) and operate under the supervision of licensed pharmacists. Look for clear contact information, a valid business registration, pharmacist credentials, and a prescription requirement process. Our platform proudly meets all these standards, giving you peace of mind with every purchase.

📞 Have more questions? Our friendly team of registered pharmacists is here to help. Reach out to us via our website chat, email, or phone — we're always happy to assist you make safe and informed decisions about your medication.

Frequently Bought Together

Brands

MSD

Active Ingredient

metformin sitagliptin 

Manufactured by

Merck Sharp & Dohme

Side Effects

As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.

Cough or hoarseness, Decreased appetite, Diarrhea, Dyspnea, Upper respiratory tract infection, Nausea, Vomiting, Flatulence, Heartburn/dyspepsia, Abdominal distention, Constipation.

Headache, Dizziness, GI disturbances, Upper respiratory tract infection, Hypoglycaemia, Joint/Muscle ache

Warning Precautions

Alcohol Warning (Not Advisable)

It is unsafe to consume alcohol with Janumet XR 100/1000mg Tablet 28s. Alcohol intoxication can increase the risk of lactic acidosis particularly in case of fasting, malnutrition or hepatic impairment.It is unsafe to consume alcohol with Janumet XR 100/1000mg Tablet 28s. Alcohol can affect the blood sugar level therefore either hyperglycemia or hypoglycemia can occur. Furthermore, it can affect the pancreas which is the site of insulin production, which in turn worsen the diabetic control.

Pregnancy Warning (Maybe Safe)

Janumet XR 100/1000mg Tablet 28s should be safe to use during pregnancy because either animal or human studies have not shown any adverse effects on the fetus, however, uncontrolled hyperglycemia in people with PCOS can increase the risk of congenital abnormalities and intrauterine death. Animal studies have shown the toxic effects at high doses on the foetuses. Due to the lack of human data, it is not recommended to use during pregnancy. Thus, please consult your doctor for more details.

Breastfeeding Warning (Limited Data)

Limited human studies suggest that Janumet XR 100/1000mg Tablet 28s does not represent a significant risk to the baby when used during pregnancy. In regards to limited data, please consult your doctor to decide on discontinuation of breastfeeding or Janumet XR 100/1000mg Tablet 28s.No academic reports explaining the use of Janumet XR 100/1000mg Tablet 28s during human lactation are available at the moment. Hence it is recommended to not use during breastfeeding.

Driving Warning (Generally Safe)

Janumet XR 100/1000mg Tablet 28s usually does not affect the ability to drive. Do not drive unless you are feeling well.Janumet XR 100/1000mg Tablet 28s usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Warning (High Risk)

Janumet XR 100/1000mg Tablet 28s is not recommended in patients with severe kidney disease, especially in patients with creatinine clearance less than 60mL/min. Patients with severe kidney disease has high risk to get lactic acidosis. Dose adjustment of Janumet XR 100/1000mg Tablet 28s and regular check up to monitor renal function may be needed. Please consult your doctor before consumption.No dose adjustment is needed for mild renal impairment patients. However, if the glomerular filtration rate is lower than 60 mL/min, dose adjustment may be needed. Please consult your doctor.

Liver Warning (Limited Data)

Janumet XR 100/1000mg Tablet 28s should be used with caution in patients with liver disease due to increased risk of lactic acidosis. Hence liver function test should be done before initiating Janumet XR 100/1000mg Tablet 28s. Discontinuation of Janumet XR 100/1000mg Tablet 28s may be needed if there is deterioration of liver function. Please consult your doctor. No dose adjustments needed in mild to moderate liver impairment whereas there are no studies on Janumet XR 100/1000mg Tablet 28s use in severe liver impairment. However, Janumet XR 100/1000mg Tablet 28s is primarily eliminated in the kidneys, so it is effects on severe liver impairment are expected to be safe.

FAQ

Disclaimer

Information last updated on: Tue Apr 14 2026 09:58:44 GMT+0000 (Coordinated Universal Time) The product images shown are for illustration purposes only and may not be an exact representation of the product.

The content provided on this webpage is to provide information only, to be fully-interpreted by a medical professional, and not intended as a guide to make purchase decisions, or a substitute to advice of a medical professional. Effectiveness and side effects of medication may differ from individual to individual. We do not encourage any customer to self-diagnose and/or self-medicate. Patients should always consult a medical professional before taking or using any medication. The content provided here is non-exhaustive and may not cover all aspects of the medication. Our service should only be used to support the doctor-patient dynamic, not replace it.

The fulfilment of prescription medication is subject to our review of a prescription issued by a Malaysian Medical Council (MMC) registered doctor. If required, we will provide a tele-consult service with one of our registered panel doctors. This is not an advertisement of a medicine as such an advertisement would require prior approval from the Medicines Advertisement Board of Malaysia. Janumet XR 100/1000mg Tablet 28s is available in many areas in Malaysia. Kuala Lumpur, Bukit Bintang, Titiwangsa, Setiawangsa, Wangsa Maju, Kepong, Segambut, Bandar Tun Razak, Cheras, Subang Jaya, Petaling Jaya, Mont Kiara, Puchong, Bandar Sunway, TTDI, Seri Kembangan, Klang, Bukit Tinggi, Damansara, Sentul, Penang, George Town, Jelutong, Gelugor, Bayan Baru, Bandar Baru Air Itam, Sungai Ara, Bukit Mertajam, Butterworth, Perai, Johor Bahru, Skudai, Bukit Indah, Gelang Patah, Senai, Pasir Gudang, Taman Daya, Taman Molek, Taman Perling, Tebrau, Danga Bay, Larkin, Nusajaya, Pontian, Masai, Setia Tropika, Desaru, Tampoi.


Janumet XR 100/1000mg Tablet 28s is available at many places in Singapore. Ang Mo Kio, Alexandra, Admiralty, Bedok, Bishan, Bukit Batok, Bukit Merah, Bukit Panjang, Bukit Timah, Boat Quay, Buona Vista, Beach Road, Bugis, Balestier, Boon Lay, Central Area, Choa Chu Kang, Clementi, Chinatown, Commonwealt, City Hall, Clarke Quay, Changi Airport, Changi Village, Clementi Park, Dairy Farm, Eunos, East Coast, Farrer Park, Geylang, Hougang, Harbourfront, Holland, Jurong, Jurong East, Jurong West, Kallang/ Whampoa, Lim Chu Kang, Marine Parade, Marina, Macpherson, Mandai, Newton, Novena, Orchard, Pasir Ris, Punggol, Potong Pasir, Paya Lebar, Queenstown, Raffles Place, Rochor, River Valley, Sembawang, Sengkang, Serangoon, Serangoon Rd, Seletar, Tampines, Toa Payoh, Tanjong Pagar, Telok Blangah, Tanglin, Thomson, Tuas, Tengah, Upper East Coast, Upper Bukit Timah, Upper Thomson, Woodlands, West Coast, Yishun, Yio Chu Kang.
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