Proglutrol G2 2/500mg SR Tablet 10s (strip)

Proglutrol G2 2/500mg SR Tablet is a combination oral antidiabetic medication containing two active ingredients — Glibenclamide 2mg and Metformin Hydrochloride 500mg — formulated as a sustained-release (SR) tablet designed to provide gradual and consistent drug delivery throughout the day. As someone looking after your health, it's good to know that this medicine belongs to the class of sulfonylurea and biguanide combination agents, which work together to help manage blood sugar levels in adults with Type 2 diabetes. Like most medicines, Proglutrol G2 may cause some side effects in certain individuals, including nausea, stomach discomfort, low blood sugar (hypoglycaemia), and diarrhoea — most of which are manageable and often improve with time. Before starting this tablet, it's important that you speak with your doctor or pharmacist, as the right dosage and suitability depend on your personal health condition and medical history. This is a prescription medicine, so always ensure you are taking it under proper medical supervision for your safety and wellbeing.

How to Take Proglutrol G2 2/500mg SR Tablet

Proglutrol G2 2/500mg SR Tablet should be taken orally with a full glass of water, preferably with meals or immediately after eating to help reduce the risk of stomach upset. As this is a sustained-release formulation, the tablet should be swallowed whole — do not crush, chew, or split it — as doing so may affect how the medicine is released into your body. Always follow your doctor's or pharmacist's specific instructions regarding the timing and frequency of your doses, and never adjust your dose on your own without professional guidance.

Dosage of Proglutrol G2 2/500mg SR Tablet

The typical recommended dose of Proglutrol G2 2/500mg SR Tablet is one tablet taken once or twice daily, as prescribed by your doctor based on your individual blood sugar control needs and tolerance. Dosage may be gradually adjusted by your healthcare provider over time, so it is important to attend regular follow-up appointments and never exceed the prescribed dose without medical advice.

Shelf Life of Proglutrol G2 2/500mg SR Tablet

Proglutrol G2 2/500mg SR Tablet generally has a shelf life of 24 to 36 months from the date of manufacture, as indicated on the product packaging. Always check the expiry date printed on the box or blister pack before use, and do not consume the tablet if it has passed its expiry date, even if it appears unchanged. Expired medicines should be disposed of safely and responsibly — do not flush them down the drain or throw them in regular household waste.

How to Store Proglutrol G2 2/500mg SR Tablet

• Store Proglutrol G2 2/500mg SR Tablet at room temperature, below 30°C
• Keep the tablets in a cool, dry place, away from direct sunlight, heat, and moisture
• Do not store in the bathroom, near the kitchen sink, or in any area with high humidity
• Keep the medicine in its original packaging with the lid tightly closed to protect it from environmental exposure
• Store out of reach and sight of children and pets at all times
• If you are unsure whether a tablet has been affected by improper storage, consult your pharmacist before taking it

Active Ingredient of Proglutrol G2 2/500mg SR Tablet

These two ingredients are combined in a single sustained-release tablet to provide a convenient and consistent dosing option for adults managing Type 2 diabetes mellitus under medical supervision.

Side Effects of Proglutrol G2 2/500mg SR Tablet

Common Side Effects:

• Nausea and vomiting
• Diarrhoea or loose stools
• Stomach pain or abdominal discomfort
• Loss of appetite
• Metallic taste in the mouth
• Headache

Side Effects Related to Low Blood Sugar (Hypoglycaemia):

• Dizziness or lightheadedness
• Sweating and shakiness
• Rapid heartbeat (palpitations)
• Hunger or weakness
• Confusion or difficulty concentrating
• Pale skin

Less Common or Serious Side Effects (Seek Medical Attention Promptly):

• Signs of lactic acidosis — unusual muscle pain, difficulty breathing, stomach pain, feeling cold, or dizziness (rare but serious)
• Skin rash, itching, or allergic reactions
• Jaundice (yellowing of the skin or eyes)
• Unusual bruising or bleeding
• Severe hypoglycaemia leading to loss of consciousness
• Low sodium levels (hyponatraemia) — confusion, seizures, or swelling

⚠️ Important: If you experience any severe or unusual symptoms, stop taking the medication and seek immediate medical attention. Always inform your doctor of any side effects you notice.

Contraindications of Proglutrol G2 2/500mg SR Tablet

• Type 1 diabetes mellitus or diabetic ketoacidosis
• Known hypersensitivity or allergy to Glibenclamide, Metformin, sulfonamides, or any excipients in the formulation
• Severe renal impairment (kidney disease) or renal failure — Metformin is contraindicated due to risk of lactic acidosis
• Hepatic impairment (liver disease) — may affect drug metabolism and increase risk of side effects
• Heart failure or conditions associated with hypoxia (low oxygen levels)
• Respiratory failure or severe pulmonary disease
• Dehydration, severe infection, or shock
• Pregnancy — not recommended; insulin is the preferred treatment during pregnancy
• Breastfeeding mothers — use is generally not advised
• Patients scheduled for iodinated contrast imaging procedures — Metformin should be temporarily discontinued
• Alcohol dependence or chronic excessive alcohol use
• Patients on MAO inhibitors or certain medications that significantly lower blood sugar

📌 This list is not exhaustive. Always consult your doctor or pharmacist to confirm that Proglutrol G2 is appropriate for your specific health condition.

Drug & Food Interactions of Proglutrol G2 2/500mg SR Tablet

Drug Interactions:

• Other antidiabetic agents (e.g., insulin, other oral hypoglycaemics) — may increase the risk of hypoglycaemia
• NSAIDs (e.g., ibuprofen, naproxen) — may enhance the blood sugar-lowering effect
• Beta-blockers (e.g., propranolol) — may mask the symptoms of hypoglycaemia
• Corticosteroids (e.g., prednisolone) — may reduce the effectiveness of the medication by raising blood sugar levels
• Diuretics (e.g., furosemide, thiazides) — may impair blood sugar control
• ACE inhibitors — may potentiate the hypoglycaemic effect
• Fluconazole and other antifungals — may increase Glibenclamide levels in the blood
• Rifampicin — may reduce the effectiveness of Glibenclamide
• Cimetidine — may increase Metformin plasma concentration
• Iodinated contrast agents — risk of acute renal failure and lactic acidosis; Metformin should be stopped before the procedure
• Alcohol — increases the risk of lactic acidosis and hypoglycaemia

Food Interactions:

• Alcohol consumption should be avoided or strictly limited while taking this medicine, as it can dangerously lower blood sugar and increase the risk of lactic acidosis
• High-sugar or high-carbohydrate foods may reduce the effectiveness of blood sugar management
• Grapefruit or grapefruit juice — limited data, but caution is advised as it may affect drug metabolism in some individuals

💡 Always inform your doctor or pharmacist about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions.

Quick Tips for Proglutrol G2 2/500mg SR Tablet

• Always take this tablet with or after food to minimise stomach-related side effects
• Swallow the SR tablet whole — never crush, break, or chew it, as this disrupts the sustained-release mechanism
• Take your dose at the same time each day to maintain consistent blood sugar levels and build a healthy routine
• Never skip or double your dose — if you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose
• Monitor your blood sugar regularly as advised by your doctor, especially when starting the medication or adjusting doses
• Carry a fast-acting sugar source (e.g., glucose tablets, sweets) with you in case of a hypoglycaemic episode
• Inform your doctor before any surgery or medical procedure, as Metformin may need to be temporarily stopped
• Store the medicine properly — in a cool, dry place below 30°C, away from sunlight and moisture
• Check the expiry date on the packaging before every use
• Keep this medicine out of reach of children at all times
• Do not share your medication with others, even if they appear to have similar symptoms
• Attend regular medical check-ups — your doctor may need to monitor your kidney function, liver function, and blood sugar levels periodically

Frequently Asked Questions (FAQs) About Proglutrol G2 2/500mg SR Tablet

Q1: Can I buy Proglutrol G2 2/500mg SR Tablet online in Malaysia?
Yes! You can purchase Proglutrol G2 2/500mg SR Tablet conveniently through our licensed online pharmacy in Malaysia. We are a registered and authorised platform, so you can shop with confidence knowing that all medicines sold through us are genuine, properly stored, and sourced from verified pharmaceutical suppliers.

Q2: Is a prescription required to purchase Proglutrol G2 2/500mg SR Tablet in Malaysia?
Yes, Proglutrol G2 2/500mg SR Tablet is a prescription-only medicine (POM) in Malaysia. As a responsible and compliant online pharmacy, we require a valid prescription from a registered medical practitioner before dispensing this product. You may be asked to upload or submit your prescription during the ordering process.

Q3: How do I know the Proglutrol G2 2/500mg SR Tablet I receive is authentic?
All products available on our platform are sourced directly from authorised distributors and licensed pharmaceutical suppliers in Malaysia. We are committed to selling only genuine, registered medicines. You can also verify the product's registration status through the National Pharmaceutical Regulatory Agency (NPRA) Malaysia database for added peace of mind.

Q4: How long does delivery take for Proglutrol G2 2/500mg SR Tablet within Malaysia?
We offer reliable delivery across Peninsular Malaysia, Sabah, and Sarawak. Standard delivery typically takes 2 to 5 working days, while express options may be available depending on your location. All orders are carefully packed to ensure the medicine is protected during transit and arrives in optimal condition.

Q5: Is it safe to order prescription medicine online from your pharmacy in Malaysia?
Absolutely. Our online pharmacy operates in compliance with Malaysian pharmaceutical regulations and guidelines. We work with licensed pharmacists who review prescription orders before dispensing, ensuring that every purchase is handled with the highest standard of care, safety, and professionalism.

Q6: What should I do if my Proglutrol G2 2/500mg SR Tablet arrives damaged or expired?
If you receive a damaged, tampered, or expired product, please contact our customer support team immediately with your order details and photos of the affected item. We take product quality very seriously and will arrange a replacement or refund in accordance with our returns policy.

Q7: Can I order Proglutrol G2 2/500mg SR Tablet in bulk or for long-term supply?
Yes, we understand that managing a chronic condition requires a consistent supply of medication. You may order a longer-term supply based on your valid prescription. However, the quantity dispensed will be guided by your prescription and our pharmacist's professional discretion to ensure safe and responsible dispensing.

Q8: How should I store Proglutrol G2 2/500mg SR Tablet after receiving my order?
Once received, store the tablets in a cool, dry place below 30°C, away from direct sunlight and humidity. Keep them in the original packaging and out of reach of children. Avoid storing in the bathroom or kitchen where moisture and heat levels may fluctuate.

Q9: What if I accidentally order the wrong product or wrong quantity?
Please contact our customer care team as soon as possible after placing your order. We will do our best to assist you before the order is processed and dispatched. Once an order has been shipped, changes may be subject to our standard returns and exchange policy.

Q10: Do you offer customer support if I have questions about my order or the medicine?
Yes, our friendly customer support team — including access to licensed pharmacists — is available to assist you with any questions related to your order, delivery, prescription submission, or product authenticity. You can reach us via our website chat, email, or phone during business hours.