Progynova 2mg Tablet

Progynova 2mg Tablet contains estradiol valerate 2mg, a form of oestrogen used in hormone replacement therapy (HRT) to relieve moderate-to-severe menopausal symptoms such as hot flashes, night sweats, vaginal dryness, and mood disturbances that occur when the ovaries reduce natural oestrogen production around and after menopause. In women who still have their womb, Progynova is typically prescribed alongside a progestogen to protect the lining of the womb from overstimulation by oestrogen alone.

As Progynova 2mg Tablet is a prescription-only hormone medicine, it is supplied through DoctorOnCall only after an online consultation with a doctor, who will review your medical history, menopausal symptoms, and personal risk factors such as history of blood clots, breast cancer, or liver disease before confirming an appropriate starting dose.

Progynova 2mg Tablet works by replenishing the body’s oestrogen (specifically estradiol) levels that decline during and after menopause, helping to reduce vasomotor symptoms such as hot flashes and night sweats, support vaginal tissue health, and maintain bone density, by restoring hormone signalling to tissues throughout the body that rely on oestrogen.

Take Progynova 2mg Tablet exactly as prescribed by your doctor, usually one tablet daily at the same time each day, swallowed whole with water; your doctor will advise whether you are on a continuous or cyclic regimen, and if you are also prescribed a progestogen, both medicines should be taken according to the specific schedule given.

The typical starting dose is one 2mg tablet daily, though your doctor may adjust this to a lower or higher strength depending on your symptom control and individual response, always aiming to use the lowest effective dose for the shortest duration needed to manage your symptoms.

Progynova 2mg Tablet is generally stable for up to 3 to 5 years from the date of manufacture when unopened, so always check the expiry date printed on the blister strip or carton before use.

Store Progynova 2mg Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the sight and reach of children.

• Known, past, or suspected breast cancer or other oestrogen-dependent cancer
• Undiagnosed abnormal vaginal bleeding
• Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
• Active or recent arterial disease such as heart attack or stroke
• Severe liver disease or liver tumours
• Known or suspected pregnancy

• Enzyme-inducing medicines such as rifampicin, certain anticonvulsants (for example carbamazepine or phenytoin), and St John’s Wort may reduce the effectiveness of Progynova 2mg Tablet
• Concurrent use with tamoxifen may reduce tamoxifen’s effectiveness and should be discussed with your doctor
• Anticoagulants such as warfarin may require closer monitoring when started or stopped alongside HRT
• Grapefruit juice may in some cases increase estradiol blood levels; discuss significant dietary changes with your doctor

• Use the lowest effective dose for the shortest duration needed to control your symptoms, as advised by your doctor
• Attend regular follow-up appointments, including breast checks and mammograms as recommended for your age group
• Report any new, unusual, or heavy vaginal bleeding to your doctor promptly
• Do not stop or adjust your dose on your own — speak to your doctor first, especially if you experience new symptoms
• Inform your doctor of any new medical conditions or medicines started while on Progynova 2mg Tablet

Progynova 2mg Tablet is generally reserved for women with moderate-to-severe menopausal symptoms who have been assessed by a doctor to have a favourable balance of benefits and risks for hormone replacement therapy. Because HRT carries risks that vary with age, time since menopause, and personal health history, DoctorOnCall’s doctors review each customer individually through an online consultation and recommend appropriate monitoring, including periodic reassessment of ongoing need.