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Duopharma Spiro 25mg Tablet 10s (strip) - DoctorOnCall Online Pharmacy

Duopharma Spiro 25mg Tablet 10s (strip)

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Prescription Required
This medication requires a valid prescription from a doctor.
Don’t Have A Prescription? Get A Consult With Our Doctor Today.
STEP 1
Checkout & review your order.
STEP 2
Make payment.
STEP 3
Our doctor will contact you within 1-hour of your purchase.
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We ensure that all our pharmaceutical products including health supplements and traditional preparations are registered with the National Pharmaceutical Regulatory Authority (NPRA) Malaysia
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CLOSE
Prescription Required
This medication requires a valid prescription from a doctor.
Don’t Have A Prescription? Get A Consult With Our Doctor Today.
STEP 1
Checkout & review your order.
STEP 2
Make payment.
STEP 3
Our doctor will contact you within 1-hour of your purchase.
Term & Condition
100% Authentic
We ensure that all our pharmaceutical products including health supplements and traditional preparations are registered with the National Pharmaceutical Regulatory Authority (NPRA) Malaysia
Free Delivery on orders above RM120
Enjoy free delivery with a minimum spend of RM120 on our platform.

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Duopharma Spiro 25mg Tablet 10s (strip) - DoctorOnCall Online Pharmacy

Duopharma Spiro 25mg Tablet 10s (strip)

RM 4.89

Product Overview

Introduction of Duopharma Spiro 25mg Tablet 10s (strip)

Duopharma Spiro 25mg Tablet is a potassium-sparing diuretic (sometimes called a "water pill") belonging to the aldosterone receptor antagonist drug class, with spironolactone as its active ingredient — manufactured right here in Malaysia by Duopharma Manufacturing (Bangi) Sdn. Bhd. and registered with the NPRA. If you have been prescribed this medicine, it is important to know that like all medications, it can cause some side effects — the most commonly reported ones include dizziness, drowsiness, fatigue, and gastrointestinal disturbances. You should always take this medication exactly as your doctor has directed, never share it with others, and inform your healthcare provider of any other medicines you are currently taking. This is a prescription-only medicine in Malaysia, so please ensure you have a valid prescription from a registered doctor before purchasing.

How to Take Duopharma Spiro 25mg Tablet

Duopharma Spiro 25mg Tablet is taken orally and should be swallowed whole with a glass of water — do not crush, chew, or break the tablet. It is best taken with food or shortly after a meal to help improve absorption and reduce the chance of stomach upset, and you should try to take it at the same time each day to maintain consistent levels in your body.

Dosage of Duopharma Spiro 25mg Tablet

The dosage of Duopharma Spiro 25mg Tablet is individually determined by your doctor based on your medical condition, severity of symptoms, and your body's response to treatment — typical doses for adults generally range from 25mg to 200mg daily, taken once or in divided doses. Always follow your doctor's prescribed dosage and never self-adjust the amount without first seeking medical advice.

Shelf Life of Duopharma Spiro 25mg Tablet

Duopharma Spiro 25mg Tablet has a shelf life as indicated on the outer packaging or blister strip. Always check the expiry date printed on the carton before use and do not consume the tablet if it has passed its expiration date. When stored correctly under the recommended conditions, the product maintains its potency and safety for the duration stated by the manufacturer.

How to Store Duopharma Spiro 25mg Tablet

Store Duopharma Spiro 25mg Tablet below 30°C in a cool, dry place away from direct sunlight, heat sources, and moisture. Keep the tablet in its original blister packaging until ready to use and ensure the product is kept out of reach of children and pets at all times. Do not store this medication in the bathroom or near the kitchen sink where humidity can affect its quality.

Active Ingredient of Duopharma Spiro 25mg Tablet

The active pharmaceutical ingredient (API) in Duopharma Spiro 25mg Tablet is Spironolactone 25mg per tablet. Spironolactone is a well-established aldosterone antagonist that has been used in clinical medicine for decades. It works by competitively blocking aldosterone receptors in the kidneys, promoting the excretion of sodium and water while retaining potassium — hence its classification as a potassium-sparing diuretic.

Side Effects of Duopharma Spiro 25mg Tablet

As with all medicines, Duopharma Spiro 25mg Tablet may cause side effects, though not everyone experiences them. Below is a list of side effects that have been reported with spironolactone-containing products:

Common Side Effects:

  • Dizziness or lightheadedness
  • Drowsiness or fatigue
  • Headache
  • Nausea, vomiting, or stomach cramping
  • Diarrhoea or gastric disturbances
  • Leg cramps
  • Electrolyte imbalances (e.g., elevated potassium — hyperkalemia)

Less Common or Hormonal-Related Side Effects:

  • Gynaecomastia (breast tissue enlargement in males)
  • Breast tenderness or pain
  • Menstrual irregularities or amenorrhoea in women
  • Hirsutism (increased facial or body hair in women)
  • Deepening of the voice in women
  • Decreased libido or erectile dysfunction in men
  • Postmenopausal vaginal bleeding

Rare but Serious Side Effects:

  • Severe allergic reactions (skin rash, urticaria, or anaphylaxis)
  • Hyponatraemia (low sodium levels in the blood)
  • Hypotension (unusually low blood pressure) with possible worsening kidney function
  • Leukopenia (reduction in white blood cell count)
  • Thrombocytopenia (low platelet count)

If you experience any serious or persistent side effects, stop taking the medication and consult your doctor or pharmacist immediately.

Contraindications of Duopharma Spiro 25mg Tablet

Duopharma Spiro 25mg Tablet is contraindicated (should NOT be used) in the following situations:

  • Patients with severe renal (kidney) impairment or complete absence of urination (anuria)
  • Patients with hyperkalemia (high potassium levels in the blood)
  • Patients with Addison's disease (adrenal insufficiency)
  • Patients who are concurrently taking eplerenone (another aldosterone antagonist)
  • Pregnancy — animal studies have shown potential reproductive toxicities; use should be avoided unless the clinical benefit outweighs the risk
  • Breastfeeding — active metabolites of spironolactone may appear in breast milk; consult your doctor before use
  • Known hypersensitivity or allergy to spironolactone or any of the inactive excipients in the formulation
  • Patients with significant hepatic (liver) impairment — use with caution and close monitoring

Patients with mild to moderate kidney impairment may still use this medication but require careful monitoring of kidney function and electrolyte levels.

Drug & Food Interaction of Duopharma Spiro 25mg Tablet

Drug Interactions:

  • ACE inhibitors (e.g., enalapril, lisinopril) and angiotensin receptor blockers (ARBs) — when combined with spironolactone, there is an increased risk of hyperkalemia (dangerously high potassium)
  • Potassium supplements or potassium-containing salt substitutes — may significantly raise potassium levels to dangerous concentrations
  • NSAIDs (e.g., ibuprofen, naproxen, aspirin) — may reduce the diuretic and blood-pressure-lowering effectiveness of spironolactone and can worsen kidney function
  • Lithium — spironolactone reduces the kidney's ability to clear lithium, increasing the risk of lithium toxicity
  • Digoxin — spironolactone and its metabolites may interfere with digoxin blood level tests, potentially leading to inaccurate readings
  • Other diuretics (e.g., amiloride, triamterene) — concurrent use may increase the risk of electrolyte disturbances
  • Cyclosporine, tacrolimus, and eplerenone — co-administration may increase risk of hyperkalemia
  • Oral contraceptives containing drospirenone — may increase potassium levels when taken with spironolactone

Food Interactions:

  • Alcohol — may intensify the dizziness and lightheadedness caused by spironolactone; avoid alcohol consumption during treatment
  • High-potassium foods (e.g., bananas, oranges, tomatoes, potatoes, coconut water) — consuming large amounts while on spironolactone may increase the risk of hyperkalemia; discuss dietary restrictions with your doctor
  • Taking the tablet consistently with food (or consistently without food) is recommended to maintain steady medication absorption

Always inform your doctor and pharmacist about all medications, supplements, and herbal products you are currently taking before starting Duopharma Spiro 25mg Tablet.

Quick Tips for Duopharma Spiro 25mg Tablet

  • Always take Duopharma Spiro 25mg Tablet exactly as prescribed by your doctor — do not self-adjust your dose or stop the medication abruptly without medical advice, as this may worsen your condition.
  • Take the tablet at the same time each day, ideally with food, to improve consistency and reduce stomach discomfort.
  • Keep a record of your medications and share the full list with all healthcare providers you visit — this helps avoid dangerous drug interactions.
  • Monitor for signs of high potassium (hyperkalemia) such as muscle weakness, irregular heartbeat, or numbness — seek medical attention immediately if these occur.
  • Avoid potassium-containing salt substitutes and reduce high-potassium foods in your diet unless otherwise instructed by your doctor.
  • Store the tablets in a cool, dry place below 30°C, away from sunlight and moisture, and in the original blister packaging.
  • Do not use the medication beyond its printed expiry date — check the packaging each time before taking a tablet.
  • Keep this medicine out of reach of children and do not share it with others, even if their symptoms seem similar to yours.
  • If you miss a dose, take it as soon as you remember — but if it is almost time for your next dose, skip the missed one and continue your usual schedule. Never double-dose.
  • Inform your doctor immediately if you are pregnant, planning to become pregnant, or breastfeeding, as this medication may not be safe to use during these periods.
  • If you experience persistent dizziness, avoid driving or operating heavy machinery until you know how this medication affects you.
  • Only purchase this prescription medication from a licensed pharmacy or verified online pharmacy to ensure product authenticity and proper dispensing.

FAQs — Duopharma Spiro 25mg Tablet

Frequently asked questions for Malaysian consumers purchasing online:

Q1: Do I need a prescription to buy Duopharma Spiro 25mg Tablet in Malaysia?

Yes. Duopharma Spiro 25mg Tablet is a prescription-only medicine (POM) in Malaysia. You will need a valid prescription issued by a Malaysian Medical Council (MMC) registered doctor to purchase this medication. Our online pharmacy requires a copy of your prescription before we can process and dispense your order.

Q2: Is Duopharma Spiro 25mg Tablet registered and legal to sell in Malaysia?

Yes. Duopharma Spiro 25mg Tablet is registered with the National Pharmaceutical Regulatory Authority (NPRA) of Malaysia under MAL registration number MAL05051106ACZ. It is legally manufactured and distributed in Malaysia by Duopharma Manufacturing (Bangi) Sdn. Bhd., a reputable Malaysian pharmaceutical company.

Q3: How can I be sure the product I receive is authentic?

We source all our pharmaceutical products directly from authorised distributors and registered manufacturers in Malaysia. Every product sold through our online pharmacy is accompanied by proper documentation and batch tracking. When you receive your order, check that the packaging is intact, the NPRA registration number is present, and the expiry date is clearly printed on the blister strip and carton.

Q4: How do I submit my prescription to purchase from your online pharmacy?

You can upload a clear photo or scanned copy of your doctor's prescription during the checkout process on our website. Alternatively, you may email or WhatsApp it to our pharmacist team for verification. All prescriptions are reviewed by our licensed pharmacists before your order is approved for dispensing.

Q5: Do you deliver Duopharma Spiro 25mg Tablet throughout Malaysia?

Yes, we offer delivery to addresses across Peninsular Malaysia, Sabah, and Sarawak. Delivery timelines may vary depending on your location. Orders within the Klang Valley typically arrive within 1–3 working days, while East Malaysia deliveries may take longer. You will receive a tracking number once your order has been dispatched.

Q6: How will my order be packaged for delivery?

All medication orders are packed in discreet, secure packaging to protect the product during transit. Temperature-sensitive products are handled with appropriate care. The product will remain in its original manufacturer blister packaging to ensure tamper-evidence and traceability.

Q7: Can I order Duopharma Spiro 25mg Tablet online and have it delivered to my home?

Yes, you can conveniently order Duopharma Spiro 25mg Tablet through our online pharmacy with home delivery available across Malaysia, subject to prescription verification. Simply add the product to your cart, upload your prescription, and our pharmacist team will review and approve your order before shipment.

Q8: How should I store the tablets once I receive my delivery?

Store your Duopharma Spiro 25mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the tablets in their original blister pack until use, and store them out of reach of children. Malaysia's tropical climate can be humid, so avoid storing the medicine in the bathroom or near the kitchen.

Q9: What should I do if my order arrives damaged or if I receive the wrong product?

Please contact our customer service team immediately if your order arrives damaged, tampered, or if an incorrect product has been sent. We will arrange for a replacement or refund in accordance with our returns policy for pharmaceutical products. Do not consume any medication that appears compromised.

Q10: Can I return or exchange Duopharma Spiro 25mg Tablet after purchase?

Due to the nature of pharmaceutical products and patient safety regulations, we are generally unable to accept returns of prescription medicines once dispensed, unless the product was received damaged, expired, or incorrect. Please contact our pharmacist team to discuss your specific situation and we will assist you accordingly.

Q11: Are there cheaper generic alternatives available on your platform?

Duopharma Spiro 25mg Tablet is itself a locally manufactured generic product containing spironolactone, offering an affordable and NPRA-approved option for patients in Malaysia. Please speak to your doctor or pharmacist about suitable options available for your condition and prescription.

Q12: How do I know if the online pharmacy I am ordering from is legitimate?

A legitimate online pharmacy in Malaysia should be licensed by the relevant Malaysian health authorities, require a valid prescription for prescription-only medicines, display pharmacist credentials, and only sell NPRA-registered products. Our platform complies with all applicable Malaysian pharmaceutical regulations to ensure your safety.

Frequently Bought Together

Brands

Duopharma

Active Ingredient

spironolactone 

Manufactured by

Duopharma Marketing Sdn Bhd

Side Effects

As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.

Drowsiness, Dizziness, Fatigue, Headache, Leg cramps, Gut disturbances, Electrolyte disturbances, Gynaecomastia, Hirsutism, Menstrual irregularities, Breast pain, Deepening of voice

Warning Precautions

Alcohol Warning (Not Advisable)

Alcohol may accentuate the dizziness, lightheadedness or fainting caused by Duopharma Spiro 25mg Tablet 10s (strip). Thus, it is not advisable to be consumed along with Duopharma Spiro 25mg Tablet 10s (strip). Please consult your doctor.

Pregnancy Warning (Not Safe)

Animal studies have shown reproductive toxicities but there are limited data on the use of Duopharma Spiro 25mg Tablet 10s (strip) in pregnant women. Thus, it is not advisable to be used during pregnancy. Please consult your doctor.

Breastfeeding Warning (Not Advisable)

Excretion of Duopharma Spiro 25mg Tablet 10s (strip) is found in small amount in human breast milk. Thus, it is not advisable to be used during breastfeeding. Please consult your doctor.

Driving Warning (Generally Safe)

Duopharma Spiro 25mg Tablet 10s (strip) usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Warning (High Risk)

Caution use and constant monitoring have to be conducted in patients with mild to moderate kidney impairment. Duopharma Spiro 25mg Tablet 10s (strip) is contraindicated in patients with severe kidney impairment. Please consult your doctor.

Liver Warning (Use With Care)

Caution use has to be practised in patients with liver impairment. Please consult your doctor.

Quick Tips

Dizziness is likely during the first several days. It should not be used until you know how it affects you. Potassium levels may rise. Do not eat or use potassium supplements. It may cause heart disease. Your doctor will monitor your kidney function and potassium levels while you are on this medication. If you see any of these symptoms, notify your doctor immediately. It may cause breast discomfort, irregular periods (women), or problems with sexual performance. Tell your doctor if you are pregnant, planning a pregnancy, or nursing.

FAQ

Disclaimer

Information last updated on: Fri Apr 03 2026 01:27:51 GMT+0000 (Coordinated Universal Time) The product images shown are for illustration purposes only and may not be an exact representation of the product.

The content provided on this webpage is to provide information only, to be fully-interpreted by a medical professional, and not intended as a guide to make purchase decisions, or a substitute to advice of a medical professional. Effectiveness and side effects of medication may differ from individual to individual. We do not encourage any customer to self-diagnose and/or self-medicate. Patients should always consult a medical professional before taking or using any medication. The content provided here is non-exhaustive and may not cover all aspects of the medication. Our service should only be used to support the doctor-patient dynamic, not replace it.

The fulfilment of prescription medication is subject to our review of a prescription issued by a Malaysian Medical Council (MMC) registered doctor. If required, we will provide a tele-consult service with one of our registered panel doctors. This is not an advertisement of a medicine as such an advertisement would require prior approval from the Medicines Advertisement Board of Malaysia. Duopharma Spiro 25mg Tablet 10s (strip) is available in many areas in Malaysia. Kuala Lumpur, Bukit Bintang, Titiwangsa, Setiawangsa, Wangsa Maju, Kepong, Segambut, Bandar Tun Razak, Cheras, Subang Jaya, Petaling Jaya, Mont Kiara, Puchong, Bandar Sunway, TTDI, Seri Kembangan, Klang, Bukit Tinggi, Damansara, Sentul, Penang, George Town, Jelutong, Gelugor, Bayan Baru, Bandar Baru Air Itam, Sungai Ara, Bukit Mertajam, Butterworth, Perai, Johor Bahru, Skudai, Bukit Indah, Gelang Patah, Senai, Pasir Gudang, Taman Daya, Taman Molek, Taman Perling, Tebrau, Danga Bay, Larkin, Nusajaya, Pontian, Masai, Setia Tropika, Desaru, Tampoi.


Duopharma Spiro 25mg Tablet 10s (strip) is available at many places in Singapore. Ang Mo Kio, Alexandra, Admiralty, Bedok, Bishan, Bukit Batok, Bukit Merah, Bukit Panjang, Bukit Timah, Boat Quay, Buona Vista, Beach Road, Bugis, Balestier, Boon Lay, Central Area, Choa Chu Kang, Clementi, Chinatown, Commonwealt, City Hall, Clarke Quay, Changi Airport, Changi Village, Clementi Park, Dairy Farm, Eunos, East Coast, Farrer Park, Geylang, Hougang, Harbourfront, Holland, Jurong, Jurong East, Jurong West, Kallang/ Whampoa, Lim Chu Kang, Marine Parade, Marina, Macpherson, Mandai, Newton, Novena, Orchard, Pasir Ris, Punggol, Potong Pasir, Paya Lebar, Queenstown, Raffles Place, Rochor, River Valley, Sembawang, Sengkang, Serangoon, Serangoon Rd, Seletar, Tampines, Toa Payoh, Tanjong Pagar, Telok Blangah, Tanglin, Thomson, Tuas, Tengah, Upper East Coast, Upper Bukit Timah, Upper Thomson, Woodlands, West Coast, Yishun, Yio Chu Kang.
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