Atomoxetine

Information About Atomoxetine

Uses of Atomoxetine

Atomoxetine is commonly used to treat attention deficit hyperactivity disorder (adhd)

How Atomoxetine Works

Atomoxetine is known to be a potent and selective inhibitor of the norepinephrine transporter (NET),2 which prevents cellular reuptake of norepinephrine throughout the brain. Positron emission tomography (PET) imaging studies have shown that atomoxetine also binds to the serotonin transporter (SERT),9 and blocks the N-methyl-d-aspartate (NMDA) receptor,10 indicating a role for the glutamatergic system

Side Effects of Atomoxetine

Decreased appetite, Headache, Somnolence, Dizziness, Abdominal pain, Nausea and vomiting, Increased blood pressure, Increased Heart Rate, Irritability, Mood swings, Dermatitis, Fatigue

Information Updated on : Mon Dec 11 2023 14:41:27 GMT+0800 (Malaysia Time)

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Atomoxetine Related Warnings

Alcohol Not Advisable

Atomoxetine may have side effects such as dizziness, somnolence and changes in pulse or heart rate. Therefore, it is not advisable to consume alcohol and the medication.

Pregnancy Not Safe

Atomoxetine may be unsafe to use during pregnancy. Animal studies and human studies do not indicate adverse effects on the fetus. However, these data are inadequate to assume that it is safe to use the medication during pregnancy. Usage is permissible in cases where benefits outweigh the risks.

Lactation Limited Data

Atomoxetine is found in rats milk. There are lack of human data suggesting that Atomoxetine is not present in human milk. Hence, taking the medication during breastfeeding should be avoided.

Driving Not advisable

Atomoxetine may cause side effects such as dizziness, fatigue, somnolence and affect pulses, all of which could affect your ability to concentrate and drive.

Kidney Safe If Prescribed

Dose adjustment of Atomoxetine is not needed in patients with kidney disease.

Liver Limited Data

Atomoxetine should be used with caution in patients with liver disease. Dose adjustment of atomoxetine may be needed especially in moderate or severe liver impairment.Please consult your doctor.

Frequently Asked Questions on Atomoxetine

FAQ

Is Atomoxetine better taken at night or in the morning?

You are advised to take Atomoxetine according to your doctor's advise. If you are meant to be taking Atomoxetine once a day, take it in the morning. If your dose of Atomoxetine is meant to be taken twice a day, take the first dose in the morning and the second dose late afternoon or early evening. This is because taking it too late in the day may cause difficulty sleeping at night and this may make you feel drowsy the following day.

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