Benserazide

Information About Benserazide

Uses of Benserazide

Benserazide is commonly used together with levodopa in the treatment of parkinson's disease.

How Benserazide Works

Benserazide is an antiparkinsonian drug that is used together with levodopa. It is a peripheral decarboxylase inhibitor which works by inhibiting the peripheral conversion of levodopa to dopamine, thus increasing the concentration of levodopa to the brain.

Side Effects of Benserazide

Nausea, Vomiting, Anorexia, Diarrhea, Taste disturbances, Cardiac arrhythmias, Orthostatic hypotension, Anxiety, Drowsiness, Depression, Agitation, Insomnia

Information Updated on : Mon Dec 11 2023 14:41:21 GMT+0800 (Malaysia Time)

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Available Medicine for Benserazide

Madopar Hbs 125mg Capsule

Madopar 250mg Tablet

Madopar 125mg Capsule

Benserazide Related Warnings

Alcohol Not Advisable

Consuming alcohol with Benserazide may further lead to side effects such as drowsiness, dizziness, nausea, vomiting and abnormal involuntary movements.

Pregnancy Not Safe

Benserazide and Levodopa has been shown toxicity towards animal fetus study but limited data on pregnant human studies suggest no risk shown. Please consult your doctor before consuming Benserazid and Levodopa during pregnancy.

Lactation Limited Data

Benserazide and Levodopa has shown no toxicity in human data of women who are breastfeeding. Precaution should be taken with doctor's advice regarding the use of Benserazide and Levodopa during breastfeeding.

Driving Not advisable

Do not drive unless you are feeling well. Benserazide may cause side effects such as sleepiness or decreased alertness, all of which could affect the ability to concentrate and drive.

Kidney Use With Care

Benserazide should be used with caution in patients with kidney disease. Dose adjustment of Benserazide may be needed. It is contraindicated in decompensated renal failure. Please consult your doctor.

Liver Limited Data

Benserazide should be used with caution in patients with liver disease. Dose adjustment of Benserazide may be needed. Please consult your doctor.

Frequently Asked Questions on Benserazide

FAQ

How does Benserazide help in treating my condition?

Benserazide has no antiparkinson actions when given alone. Benserazide is always given alongside Levodopa (anti parkinson medication) and works by preventing Levodopa from being broken down before it reaches the brain. It does not treat the symptoms itself, but rather it decrease the unpleasant side effect of Levodopa.

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