Brinzolamide

Information About Brinzolamide

Uses of Brinzolamide

Brinzolamide is commonly used to treat glaucoma, ocular hypertension

How Brinzolamide Works

Brinzolamide works by inhibiting the carbonic anhydrase which leads to decreased aqueous humor secretion. This results in a reduction of intraocular pressure.

Side Effects of Brinzolamide

Blurred vision, Dry eyes, Headache, Eye pain, Itchiness of the eye, Taste abnormality, Watery eye

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Brinzolamide Related Warnings

Alcohol Safe

It is not known whether alcohol consumption will interact with Brinzolamide. There is no adverse reaction recorded involving these two substances together. It is, therefore, safe to be used together.

Pregnancy Not Safe

Animal reproductive studies have shown fetal toxicity while there are no or inadequate data involving human pregnancy. It is advisable for pregnant women to use other alternatives for the eye problems.

Lactation Limited Data

It is not known whether Brinzolamide is excreted through the human breastmilk or not. Animal studies have shown traces of breastmilk when Brinzolamide was given orally. The decision to use Brinzolamide depends on the risk to benefit of the treatment to the infant and the mother.

Driving Not advisable

It is not advisable to drive while using Brinzolamide due to its possible side effects to the eyes such as blurred vision and eye pain which can affect the concentration and ability to drive.

Kidney High Risk

Dose adjustment may be needed in those with mild to moderate renal impairment while it is contraindicated in severe kidney disease.

Liver Limited Data

Brinzolamide has not been studied on the effect of hepatic impaired patient. It does not have any contraindication or reported adverse effects involving the liver previously, therefore, the uses should be used only when indicated and advice from a specialist.