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Bumetanide is commonly used to treat oedema
Bumetanide works by inhibiting the absorption of sodium and chloride ions in the kidney. As a result, water will follow sodium and chloride to be excreted into the urine.
Abdominal pain, Nausea, Vomiting, Headache, Diarrhea, Dehydration, Skin rash, Itchiness, Painful breast, Breast enlargement
There is no contraindication nor any pervious data to suggest interaction between Bumetanide and alcohol. The side effects profile of Bumetanide also does not suggest any augmentation of the alcohol side effects.
Animal studies have shown some adverse reaction on the reproduction while there is no human pregnancy data to dismiss the possibility of side effects to the fetal or mother using Bumetanide. Doctor's advice should be sought before using Bumetanide in pregnancy.
There is no data to indicate any traces of Bumetanide in the human breastmilk. It is advisable to stop using Bumetanide when the mother want to breastfeed the infant unless it is necessary.
Bumetanide has no known effect on the ability to drive or operate machinery.
In people with renal impairment, dosage adjustment may be required. In severe renal impairment, larger doses are needed to achieve similar therapeutic effect and should be under constant monitoring.
Bumetanide may precipitate encephalopathy in hepatic impaired patient. Dosage adjustment may be needed as well as close monitoring.
