Cefaclor

Information About Cefaclor

Uses of Cefaclor

Cefaclor is commonly used to treat bacterial infections, bacterial infections of urinary tract, ear infection, pneumonia, respiratory tract infection, skin infections

How Cefaclor Works

Cefaclor works by binding to the Penicillin-Binding Proteins to inhibit the final step of transpeptidation of the peptidoglycan synthesis of the bacterial cell wall. This results in failure of cell wall synthesis which ultimately leads to the death of the bacteria.

Side Effects of Cefaclor

Diarrhea, Nausea, Vomiting, Rash, Headache, Joint pains, Fever, Hypersensitivity reaction

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Cefaclor Related Warnings

Alcohol Safe

There is no contraindication on the consumption of alcohol with Cefaclor suggested by any previous clinical data.

Pregnancy Maybe Safe

Animal studies have been shown to be safe for fetal development but no adequate data to suggest the same on human pregnancy study or to suggest harm either. Caution should be taken when commencing someone on Cefaclor during pregnancy.

Lactation Limited Data

Small amount of Cefaclor traces has been detected in human breastmilk but no adequate data to suggest harm to the nursing infants. It is therefore advisable to take precautionary measures when taking Cefaclor.

Driving Generally Safe

Cefaclor is safe to be used before driving as no side effects profile are known to cause impairment in the concentration level of driving or operating machinery.

Kidney Use With Care

Cefaclor should be used with caution in people with severe renal impairment and dosage adjustment may be needed. No dosage adjustment is needed, however, in people with mild to moderate renal impairment.

Liver Limited Data

There is no dosage adjustment or contraindication for people with hepatic impairment according to the manufacturer labelling.