Ceftazidime

Information About Ceftazidime

Uses of Ceftazidime

Ceftazidime is commonly used to treat bacterial infections, typhoid fever

How Ceftazidime Works

Ceftazidime works by binding to the Penicillin-Binding Proteins to inhibit the final step of transpeptidation of the peptidoglycan synthesis of the bacterial cell wall. This results in failure of cell wall synthesis which ultimately leads to the death of the bacteria.

Side Effects of Ceftazidime

Metallic taste, Headache, Dizziness, Diarrhea, Nausea, Vomiting, Abdominal pain, Itchiness, Skin rash, Fever, Allergic reaction

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ceftazidime Related Warnings

Alcohol Safe

There is no contraindication on the consumption of alcohol with Ceftazidime suggested by any previous clinical data.

Pregnancy Maybe Safe

Animal studies have been shown to be safe for fetal development but no adequate data to suggest the same on human pregnancy study or to suggest harm either. Caution should be taken when commencing someone on Ceftazidime during pregnancy.

Lactation Safe If Prescribed

Ceftazidime is excreted into the human breastmilk and it is not anticipated to cause the infant any harm when Cetazidime is given at therapeutic dose to the mother. It is, therefore, can be used during breastfeeding.

Driving Not advisable

It is not advisable to drive or operate machinery when taking Ceftazidime due to its potential side effects such as dizziness and headache which can affect concentration and ability to drive.

Kidney Use With Care

Ceftazidime is excreted by the kidneys and dosage adjustment is advisable for people with renal impairment.

Liver Safe If Prescribed

There is no dosage adjustment or contraindication for people with hepatic impairment according to the manufacturer labelling. However, close clinical monitoring is advisable.