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Chloramphenicol

Information About Chloramphenicol

Uses of Chloramphenicol

Chloramphenicol is commonly used to treat bacterial, eye, ear infections as well as meningitis.

How Chloramphenicol Works

Chloramphenicol is an antibiotic. It works by binding to the site of protein synthesis, specifically the 50s subunit protein of the bacteria's ribosome. Thus, it causes the destruction of bacterial proteins.

Side Effects of Chloramphenicol

GI symptoms; bleeding; peripheral and optic neuritis, visual impairment, blindness; encephalopathy, confusion, delirium, mental depression, headache. Haemolysis in patients with G6PD deficiency, Hypersensitivity reactions (rashes, fever and angioedema) Eye drop: Blurred vision. Ear drops: Ototoxicity.

Information Updated on : Mon Dec 11 2023 14:40:52 GMT+0800 (Malaysia Time)

Chloramphenicol Related Warnings

Alcohol Safe

It is safe to have alcohol with Chloramphenicol

Pregnancy Not Safe

Chloramphenicol is not recommended in pregnant women. Some animal studies have shown side effects on the foetus, however, there are limited human studies. Benefits may outweigh the risk in pregnant woman so please consult your doctor.

Lactation Not Advisable

Chloramphenicol is contraindicated to patients who are currently breastfeeding as Chloramphenicol is excreted in the breastmilk and have cause adverse effects to breastfed infant such as loss of appetite and heavy vomitting.

Driving Not advisable

It is not advised to drive after taking Chloramphenicol, especially if medication is taken in the form of eye drops as it may blur your vision causing disruption to the driver.

Kidney Use With Care

Chloramphenicol should be used with caution in patients with significantly impaired renal disease kidney disease. Dose adjustments may be needed. Please consult your doctor before using it.

Liver Use With Care

Chloramphenicol should be used with caution in patients with significantly impaired liver disease. Dose adjustments may be needed. Please consult your doctor before using it.

Frequently Asked Questions on Chloramphenicol

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