Clobetasone butyrate

Information About Clobetasone butyrate

Uses of Clobetasone butyrate

Clobetasone butyrate is commonly used to treat severe allergic reactions such as atopic dermatitis, irritant or allegic dermatitis, nappy rash, photodermatitis and contact dermatitis. it is also used to treat skin disorders such as prurigo nodularis and insect bite reactions.

How Clobetasone butyrate Works

Clobetasone Butyrate is a synthetic glucocorticoid. It suppresses inflammatory mediators such as prostaglandin, leukotrienes and others by inducing phospholipase A2 inhibitory proteins (lipocortins) and sequentially inhibits the release of arachidonic acid.

Side Effects of Clobetasone butyrate

Itchy skin, Burning sensation of the skin, Skin redness, Skin dryness and irritation , Papular rashes and folliculitis, Acne , Hypopigmentation, Secondary infection, Skin atrophy, Striae

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Clobetasone butyrate Related Warnings

Alcohol Safe

It is safe to consume alcohol with Clobetasone Butyrate. There is no interaction between alcohol and the medication.

Pregnancy Not Safe

Clobetasone Butyrate may be unsafe to use during pregnancy as animal studies have shown adverse effects on foetal development, however, no data on human studies. Usage is permissible if benefits to the mother outweigh the risk to the fetus.

Lactation Limited Data

Clobetasone Butyrate is not safe to use during lactation as there is no information regarding the presence of the medication in human milk. Nevertheless, do not apply to the breasts topically to avoid ingestion by the infant.

Driving Generally Safe

Clobetasone Butyrate has no ability to influence the general attention during driving.

Kidney Safe If Prescribed

Dose adjustment is required in case of systemic absorption when application is over a large surface area for a prolonged period as there is a higher risk of systemic toxicity.

Liver Limited Data

Dose adjustment of Clobetasone Butyrate is required in case of systemic absorption when application is over a large surface area for a prolonged period as there is a higher risk of systemic toxicity.