Desvenlafaxine

Information About Desvenlafaxine

Uses of Desvenlafaxine

Desvenlafaxine is commonly used to treat depression.

How Desvenlafaxine Works

Desvenlafaxine is a Selective Serotonin and Norepinephrine Reuptake Inhibitor (SNRI). Thus, Desvenlafaxine restores serotonin and norepinephrine levels in the brain.

Side Effects of Desvenlafaxine

Constipation, Dizziness, Drowsiness, Insomnia, Nausea, Decreased appetite, Sweating profusely, Dry mouth, Sexual function disorders in males, Rash

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Desvenlafaxine Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Desvenlafaxine. Taking Desvenlafaxine with alcohol may potentiate side effects of dizziness, drowsiness, and difficulty concentrating.

Pregnancy Not Safe

Desvenlafaxine may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor before using it.

Lactation Limited Data

As Desvenlafaxine is excreted into human breast milk, there could be a potential adverse effects in nursing infants. Decision to discontinue breastfeeding or to discontinue treatment should be discussed with your doctor. Its benefits could outweigh the possible risks.

Driving Generally Safe

Desvenlafaxine doesn't significantly impair your concentration and ability to drive. However, avoid driving if experiencing dizziness or drowsiness.

Kidney Use With Care

Desvenlafaxine should be used with caution in patients with kidney disease. Dose adjustment of Desvenlafaxine may be needed in those with moderate and severe renal impairment. It is not to be used in patients with kidney failure. Please consult your doctor before using it.

Liver Limited Data

Less than 5% of an administered dose of DV is metabolized in the liver hence dose adjustment of Desvenlafaxine may not be needed. Nonetheless, Desvenlafaxine should be used with caution in patients with moderate to severe liver disease. Please consult your doctor before using it.