Dipyridamole

Information About Dipyridamole

Uses of Dipyridamole

Dipyridamole is commonly used to treat blood clot formation after cardiac valve replacement as well as prevention of heart attack and stroke.

How Dipyridamole Works

Dipyridamole inhibits adenosine deaminase and phosphodiesterase along the pathway of platelet aggregation. In addition, Dipyridamole has vasodilating properties through the accumulation of prostacyclin or prostaglandin-2.

Side Effects of Dipyridamole

Angina pectoris, Hypotension, Headache, Dizziness, Diarrhea, Nausea, Vomiting, Rash, Muscle ache, Risk of bleeding

Information Updated on : Mon Apr 22 2024 15:52:19 GMT+0800 (Malaysia Time)

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Dipyridamole Related Warnings

Alcohol Not Advisable

It is not advisable to take alcohol simultaneously with Dipyridamole. Alcohol can potentiate the side effects of headache and dizziness caused by Dipyridamole.

Pregnancy Maybe Safe

Dipyridamole may be unsafe to use during pregnancy. Animal studies have not shown adverse effects on the fetus, however, there are limited human studies. Please consult your doctor before using it as its benefits may outweigh the risk of usage in a pregnant woman.

Lactation Limited Data

Dipyridamole is excreted into breast milk. However, its effect on the feeding baby is largely unknown. Hence, the decision to discontinue Dipyridamole or stop breastfeeding is to be done after consulting your doctor.

Driving Not advisable

Dipyridamole may cause side effects of dizziness and headaches all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Kidney Safe If Prescribed

Renal excretion of Dipyridamole is low and studies have shown no change in its metabolism when used in patients with kidney disease of varying degrees. However, please consult your doctor before using it.

Liver Limited Data

Dipyridamole should be used with caution in patients with clinically known liver disease. Dose adjustment of Dipyridamole may be needed. Please consult your doctor before using it.

Frequently Asked Questions on Dipyridamole

FAQ

Does Dipyridamole affect blood pressure?

Dipyridamole may rarely cause a decrease in blood pressure as a side effect. It is advised to consult your doctor if you experience lightheadedness, dizziness, blurred vision or feel weak. It is best to contact your doctor immediately if you experience these side effects.

Can the use of Dipyridamole cause bleeding?

It is possible that Dipyridamole can increase the risk of bleeding. It is best that you are always careful while doing activities that can result in injuries. Consult your doctor if you experience any abnormal bleeding or bruising.

Should Dipyridamole be stopped before surgery?

Yes, your doctor may advise you to stop taking Dipyridamole few days prior to surgery. The reason being that Dipyridamole increases the risk of bleeding and may lead to excessive bleeding during surgery.

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