Fluoxetine

Information About Fluoxetine

Uses of Fluoxetine

Fluoxetine is commonly used to treat anxiety disorder, bipolar depression, depression, obsessive compulsive disorder, post traumatic stress disorder

How Fluoxetine Works

Fluoxetine works by inhibiting the reuptake of serotonin at the presynaptic membrane which results in increase concentration of serotonin at the synapse.

Side Effects of Fluoxetine

Insomnia, Restlessness, Sleep disorder, Abnormal dreams, Headache, Dizziness, Blurred vision, Dry mouth, Erectile dysfunction

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Fluoxetine Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Fluoxetine. Taking Fluoxetine with alcohol may potentiate side effects of dizziness, drowsiness, and difficulty concentrating.

Pregnancy Not Safe

There is a risk to fetal development having Pulmonary Hypertension based on previous epidemiological data. The use of Fluoxetine is only indicated if the benefits outweigh the risk.

Lactation Not Advisable

It is known that Fluoxetine and its metabolite are excreted into the human breastmilk and it is not advisable to breastfeed when taking Fluoxetine.

Driving Not advisable

It is not advisable to drive when taking Fluoxetine due to its potential side effects such as headache and dizziness which can affect the ability to drive and concentrate.

Kidney Use With Care

Fluoxetine is excreted via urine and dosage adjustment may be needed in patients with renal impairment.

Liver Use With Care

Fluoxetine is metabolised extensively by the liver and dosage adjustment is advisable for patient with hepatic impairment.