Galantamine

Information About Galantamine

Uses of Galantamine

Galantamine is commonly used to treat alzheimer's disease, dementia in parkinson's disease

How Galantamine Works

Galantamine works by competitively and reversibly inhibit the enzyme acetylcholinesterase hence increases the availability of acetylcholine to the nicotinic receptor of the central nervous system.

Side Effects of Galantamine

Abdominal pain, Slow pulse, Diarrhea, Dizziness, Fatigue, Hallucination, Headache, Nausea, Blackout, Tremor

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Galantamine Related Warnings

Alcohol Not Advisable

Consuming alcohol when taking Galantamine may potentiates the adverse effects of Galantamine such as dizziness and nausea.

Pregnancy Not Safe

Animal studies have shown reproductive toxicity while there is no adequate human pregnancy data to state otherwise. Caution should be taken if Galantamine is to be used during pregnancy.

Lactation Limited Data

It is not known whether Galantamine is excreted into human breastmilk or not thus it is not advisable to breastfeed during the treatment period.

Driving Not advisable

It is not advisable to drive when taking Galantamine due to its potential side effects such as headache and dizziness which can affect the ability to drive and concentrate.

Kidney High Risk

Dosage adjustment may be needed in mild to moderate renal impaired patients and is contraindicated to be used in patients with severe renal impairment.

Liver Limited Data

Dosage adjustment is advisable for patients with mild to moderate hepatic impairment and contraindicated in patients with severe hepatic impairment.