Glycopyrrolate

Information About Glycopyrrolate

Uses of Glycopyrrolate

Glycopyrrolate is commonly used to treat drooling or excessive salivation, arrhythmia such as bradycardia and it is also used as anesthesia.

How Glycopyrrolate Works

Glycopyrrolate is an antimuscarinic. It prevents the stimulation of acetylcholine receptors by inhibiting the action of acetylcholine at parasympathetic sites in smooth muscle, secretory glands, and the central nervous system which indirectly reduces the rate of salivation.

Side Effects of Glycopyrrolate

Flushing, Headache, Vomiting, Dry mouth, Constipation, Nasal congestion, Agitation and aggressive, Pallor, Palpitation, Dry skin

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Glycopyrrolate Related Warnings

Alcohol Safe

It is safe to consume alcohol and glycopyrrolate as there is no identified drug interaction.

Pregnancy Not Safe

Glycopyrrolate may be unsafe to use during pregnancy as there are limited human studies that have shown adverse effects on fetus. Nevertheless, it does not appear to penetrate through the placental barrier in significant amounts. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Lactation Safe If Prescribed

It is found in breast milk at small amount. It is too small to give harmful effects.

Driving Not advisable

It is unsafe to be used when driving as it can affect your eyesight thus affecting your ability to drive.

Kidney Use With Care

Glycopyrrolate should be used with caution in patients with severe kidney disease as elimination is severely impaired.Thus, please consult your doctor as dosage adjustment is needed.

Liver Safe If Prescribed

Glycopyrrolate should be used with caution in patients with liver disease and dose adjustment may be needed. Please consult your doctor.