Hydrochlorothiazide

Information About Hydrochlorothiazide

Uses of Hydrochlorothiazide

Hydrochlorothiazide is commonly used to treat high blood pressure, acute heart failure, hypertension, kidney stone, oedema,

How Hydrochlorothiazide Works

Hydrochlorothiazide works by inhibiting the reabsorption of Na in the distal tubules causing increased excretion of Sodium Na, water H2O, potassium K and hydrogen ions.

Side Effects of Hydrochlorothiazide

High potassium level, High uric acid level, Difficulty sleeping (insomnia), Dizziness, Somnolence, Palpitations, Chest pain, Vasodilation, Cough, Back pain, Fatigue

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Hydrochlorothiazide Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Hydrochlorothiazide as there is a risk of additive effect such lowering blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate

Pregnancy Maybe Safe

Both animal studies and human studies are insufficient to show adverse effects on the fetus. Pregnant women may use it if the benefits outweigh the risks. Please consult your doctor.

Lactation Not Advisable

Hydrochlorothiazide is excreted in human milk. It also reduces milk production due to it diuresis effect.

Driving Not advisable

The usage of Hydrochlorothiazide may impair general attention and affect the ability to drive as it can cause side effects such as dizziness, somnolence and palpitations.

Kidney Use With Care

Dose adjustment is required in patients with kidney disease. In patients with severe renal function, use is not recommended. Please consult your doctor.

Liver Use With Care

Hydrochlorothiazide should be used with caution in patients with liver disease as it may precipitate hepatic coma.