Hydroxychloroquine

Information About Hydroxychloroquine

Uses of Hydroxychloroquine

Hydroxychloroquine is commonly used to treat psoriatic arthritis, rheumatoid arthritis, systemic lupus erythematosus (sle) and discoid erythematosus. it is also used as antimalaria agent and in prevention of malaria.

How Hydroxychloroquine Works

Hydroxychloroquine interferes with the ability for Malaria to metabolise and utilise red blood cell. The mechanism of action in the treatment of autoimmune conditions like rheumatoid arthritis and lupus erythematosus has not been fully elucidated.

Side Effects of Hydroxychloroquine

Palpitations, Chest pain, Weight loss, Frequent falls, Dizziness, Headache, Nightmare, Itchy and red skin, Progressive weakness

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Hydroxychloroquine Related Warnings

Alcohol Not Advisable

There is no known drug interaction between alcohol and hydroxychloroquine. Nevertheless, special precautions should be taken into consideration if patient has an issue with alcoholism.

Pregnancy Limited Data

Hydroxychloroquine should not be used during pregnancy as it has been associated with central nervous system damage, including ototoxicity (auditory and vestibular toxicity, congenital deafness), retinal hemorrhages and abnormal retinal pigmentation.

Lactation Not Advisable

Hydroxychloroquine is probably unsafe to use during lactation as it is excreted in small quantity in human milk and infant is very sensitive to the medication.

Driving Not advisable

Hydroxychloroquine may cause side effects such as dizziness, headaches, tiredness, all of which could affect your ability to concentrate and drive.

Kidney Use With Care

Hydroxychloroquine should be used with caution in patients with kidney disease. Dose adjustment may be needed and renal function should be monitored frequently. Please consult your doctor.

Liver Use With Care

In patients with liver disease, Hydroxychloroquine should be used with caution. dose adjustment of Hydroxychloroquine may also be required. Please consult your doctor.