Linagliptin

Information About Linagliptin

Uses of Linagliptin

Linagliptin is commonly used to treat type 2 diabetes mellitus

How Linagliptin Works

Linagliptin inhibits an enzyme, dipeptidyl peptidase-4 (DPP-4) which is involved in the inactivation of the incretin hormones causing it to become more active and higher in concentration.

Side Effects of Linagliptin

Low sugar level, Severe joint pain, Rash, Mouth ulcer, Diarrhea, Cough

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Linagliptin Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Linagliptin as there is no information regarding Linagliptin interactions.

Pregnancy Limited Data

Use of linagliptin should be avoided during pregnancy. Animal studies have shown no adverse effects on the fetus, and it is not yet being studied in pregnant women.

Lactation Not Advisable

A risk to nursing infant cannot be excluded as there is no information regarding the excretion in human milk. Therefore, Linagliptin is probably unsafe to use during lactation.

Driving Not advisable

Linagliptin has no or negligible influence on the ability to drive. Nevertheless, patients should be alerted to the risk of low blood sugar if it is taken with sulphonylurea or insulin.

Kidney Safe If Prescribed

Linagliptin can be used in patients with kidney disease. No dose adjustment of Linagliptin may be needed. Please consult your doctor.

Liver Use With Care

Linagliptin can be used with caution in patients with liver disease. No dose adjustment of Linagliptin may be needed. Please consult your doctor.