Naltrexone

Information About Naltrexone

Uses of Naltrexone

Naltrexone is commonly used to treat alcohol addiction and opioid dependence

How Naltrexone Works

Naltrexone inhibits the action of opioids by acting as a competitive inhibitor at the opioids receptor site. This action precipitates opioids withdrawal symptoms in opioids dependent individuals.

Side Effects of Naltrexone

Pain in the abdomen, Nausea & Vomiting, Diarrhea, Constipation, Feeling anxious, Insomnia, Headache, Muscle pain, Chest pain, Chills, Dizziness

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Naltrexone Related Warnings

Alcohol Not Advisable

Naltrexone is used to treat alcohol addiction. Taking Naltrexone with alcohol will accentuate the withdrawal symptoms of opioids and makes the patients feeling worst.

Pregnancy Not Safe

Study of Naltrexone administration in the animal has shown some adverse effects to the pregnant mother and embryo. However, no controlled studies had been done in humans. Administration of this medication during pregnancy should only be done only if the benefits outweigh the risks.

Lactation Limited Data

No data are available for the safety of Naltrexone use during breastfeeding. It is unknown whether this medication is excreted in breast milk. It is not recommended to use this medication while breastfeeding.

Driving Not advisable

Naltrexone may cause a significant effect on the psychological & physical abilities of the user. Therefore avoid driving or operating machines while taking this medication.

Kidney High Risk

Naltrexone is contraindicated in patients with severe kidney impairment

Liver Limited Data

Naltrexone is contraindicated in patients with severe liver impairment