Permethrin

Information About Permethrin

Uses of Permethrin

Permethrin is commonly used to treat filariasis, head lice, onchocerciasis itchy bumps on the skin, scabies, and strongyloidiasis.

How Permethrin Works

It is a pyrethrin pediculocide and scabicide that treats parasite and fungal infection and also scabies. It interrupts Na ion influx through nerve cell membrane channels, delaying repolarisation and cause the parasites to paralyse and die.

Side Effects of Permethrin

Skin itchiness, Skin redness, Skin swelling, Burning or tingling sensation.

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Permethrin Related Warnings

Alcohol Safe

It is safe to consume alcohol with Permethrin because it is a topical drug. Ovicidal activity of Permethrin is increased by addition of an alcohol.However, if you feel any unfamiliar reactions when taking Permethrin with alcohol, please consult your doctor.

Pregnancy Maybe Safe

Permethrin may be safe to use during pregnancy. Animal studies do not show any adverse effects on the fetus, however, there are limited human studies. Please consult your doctor.

Lactation Limited Data

it is not known whether permethrin is excreted in human milk even though in cattle, low concentrations are excreted in the milk. Limited human data suggests that Permethrin does not represent a significant risk to the baby. Users should consider withholding treatment during nursing temporarily.

Driving Generally Safe

Permethrin usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Safe If Prescribed

There's no increased risk of toxic reactions in patients with renal impairment using Topical Permethrin as Permethrin is metabolized in liver and excreted in urine as inactive metabolite. Please consult your doctor.

Liver Limited Data

There is a hepatic metabolism of Permethrin, hence dose adjustment of Permethrin may be needed. Please consult your doctor.