Prasugrel

Information About Prasugrel

Uses of Prasugrel

Prasugrel is commonly used to treat heart attack as future heart attack prevention or known as acute coronary syndromes such as unstable angina and myocardial infarction

How Prasugrel Works

Prasugrel inhibits platelets activation and aggregation by irreversibly blocks the P2Y12 component of adenosine diphosphate (ADP) receptors on the platelet

Side Effects of Prasugrel

Headache, Backpain, Dyspnoea, Dizziness, Angioedema, Cough, Hypotension, Bradycardia, Fatigue, Diarrhea, Rash

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Prasugrel Related Warnings

Alcohol Not Advisable

It is not recommended to consume alcohol while taking this medication.

Pregnancy Maybe Safe

Animal studies show that Prasugrel does not carry harmful effect towards embryo or foetal development as well as towards the pregnancy itself. However, as human studies have never been conducted, Prasugrel can only be used in pregnancy only if the benefits outweigh the risks.

Lactation Limited Data

Animal studies show that this medication is excreted in breast milk. No human data available, therefore this medication is not recommended to be used in breastfeeding.

Driving Generally Safe

Prasugrel has not shown to cause impairment in the ability to drive or operate machines. However, only drive if you are feeling well.

Kidney Safe If Prescribed

Prasugrel is safe to use in patients with kidney impairment

Liver Limited Data

No dose adjustment needed in patients with mild to moderate kidney impairment but is contraindicated in patients with severe hepatic impairment