Repaglinide

Information About Repaglinide

Uses of Repaglinide

Repaglinide is commonly used to treat type 2 diabetes mellitus

How Repaglinide Works

Repaglinide is a short-acting meglitinide which is able to block the ATP-dependent potassium channels in Beta-cell membranes.

Side Effects of Repaglinide

Hypoglycaemia, Acute coronary syndrome, Abdominal pain, Diarrhea, Joint pain, Back pain, Headache, Increased risk of infection

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Repaglinide Related Warnings

Alcohol Not Advisable

Alcohol may accentuate the hypoglycaemic effect caused by Repaglinide. Thus, it is not advisable to consume alcohol with Repaglinide concomitantly.

Pregnancy Not Safe

There are no data on the use of Repaglinide in pregnant women. Thus, it is not advisable to be used during pregnancy.

Lactation Limited Data

There are no data on the use of Repaglinide in breastfeeding women. Thus, it is not advisable to be used during breastfeeding.

Driving Generally Safe

Repaglinide usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

Dose adjustment is needed in patients with severe kidney impairment. Please consult your doctor.

Liver Limited Data

Caution use has to be practised in patients with liver impairment as there are no clinical studies conducted in this group of patients. Please consult your doctor.