Ropinirole

Information About Ropinirole

Uses of Ropinirole

Ropinirole is commonly used to treat parkinson's disease and restless leg syndrome.

How Ropinirole Works

Ropinirole is a non-ergot dopamine agonist which has a higher affinity for D3 receptors which are located in the brain. It is able to increase the dopamine level and enhance the dopaminergic activity

Side Effects of Ropinirole

Sudden sleepiness, Drowsiness, Nausea, Abdominal pain, Dizziness, Headache, Hallucinations, Abnormal movements

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ropinirole Related Warnings

Alcohol Not Advisable

Alcohol may accentuate the sedative effect caused by Ropinirole. Thus, it is not advisable to consume alcohol and Ropinirole concomitantly.

Pregnancy Not Safe

Animal studies have shown reproductive toxicities but there are limited data on the use of Ropinirole in pregnant women. Thus, it is not advisable to be used during pregnancy as risks cannot be excluded.

Lactation Not Advisable

Ropinirole decreases the prolactin secretion in human, which will lead to the suppression of milk production. Thus, it should be discontinued during breastfeeding.

Driving Not advisable

Do not drive unless you are feeling well. Ropinirole may cause side effects such as impaired alertness, drowsiness or sleepiness, all of which could affect your ability to concentrate and drive.

Kidney Use With Care

Dose adjustment is needed in patients with severe kidney impairment. It is contraindicated in patients with end-stage kidney disease under dialysis. Please consult your doctor.

Liver Use With Care

Caution use has to be practised in patients with moderate liver impairment. Ropinirole is contraindicated in patients with severe liver impairment.