Spironolactone

Information About Spironolactone

Uses of Spironolactone

Spironolactone is commonly used to treat heart failure, liver cirrhosis with edema, potassium deficiency, nephrotic syndrome, oedema

How Spironolactone Works

Spironolactone is a potassium-sparing diuretic which is able to inhibit the aldosterone dependant sodium-potassium exchange channels in kidneys leading to increased excretion of sodium and water without affecting the potassium level.

Side Effects of Spironolactone

Drowsiness, Dizziness, Fatigue, Headache, Leg cramps, Gut disturbances, Electrolyte disturbances, Gynaecomastia, Hirsutism, Menstrual irregularities, Breast pain, Deepening of voice

Information Updated on : Mon Dec 11 2023 14:40:32 GMT+0800 (Malaysia Time)

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Available Medicine for Spironolactone

Duopharma Spiro 25mg Tablet

Spironolactone Related Warnings

Alcohol Not Advisable

Alcohol may accentuate the dizziness, lightheadedness or fainting caused by Spironolactone. Thus, it is not advisable to be consumed along with Spironolactone. Please consult your doctor.

Pregnancy Not Safe

Animal studies have shown reproductive toxicities but there are limited data on the use of Spironolactone in pregnant women. Thus, it is not advisable to be used during pregnancy. Please consult your doctor.

Lactation Not Advisable

Excretion of Spironolactone is found in small amount in human breast milk. Thus, it is not advisable to be used during breastfeeding. Please consult your doctor.

Driving Generally Safe

Spironolactone usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney High Risk

Caution use and constant monitoring have to be conducted in patients with mild to moderate kidney impairment. Spironolactone is contraindicated in patients with severe kidney impairment. Please consult your doctor.

Liver Use With Care

Caution use has to be practised in patients with liver impairment. Please consult your doctor.

Frequently Asked Questions on Spironolactone

FAQ

Can I stop taking Spironolactone if my blood pressure is under control?

No, you should not stop taking Spironolactone even if your blood pressure is controlled. It is usually prescribed for long term and sudden discontinuation of this medication may worsen your condition. Consult your doctor if you are experiencing any side effects or if you want to stop taking Spironolactone. Your doctor may be able to prescribe a different medicine for controlling your blood pressure.

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