Tenofovir disoproxil fumarate

Information About Tenofovir disoproxil fumarate

Uses of Tenofovir disoproxil fumarate

Tenofovir disoproxil fumarate is commonly used to treat chronic hepatitis b virus hbv infection, hiv infection

How Tenofovir disoproxil fumarate Works

Tenofovir disoproxil fumarate is an antiviral which is able to inhibit the nucleotide reverse transcriptase, an essential enzyme for viral production

Side Effects of Tenofovir disoproxil fumarate

Gut disturbances, Dizziness, Headache, Nausea and vomiting Diarrhea, Abdominal discomfort, Liver enzyme dysfunction, Skin rash, Hypophosphataemia, Lactic acidosis

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Tenofovir disoproxil fumarate Related Warnings

Alcohol Not Advisable

There is no known interaction between alcohol and Tenofovir disoproxil fumarate when used concomitantly. However, alcohol consumption can increase the risk of liver damage, further accentuate the side effect of Tenofovir disoproxil fumarate on the liver. Thus, alcohol is not advisable to be used concomitantly with Tenofovir disoproxil fumarate.

Pregnancy Maybe Safe

Human studies and animal studies do not show reproductive toxicities. Thus, Tenofovir disoproxil fumarate can be used during pregnancy if indicated. Please consult your doctor.

Lactation Not Advisable

Human studies have shown the excretion of Tenofovir disoproxil fumarate in breastmilk but there are limited data on the effects of Tenofovir disoproxil fumarate in breastfed babies. Thus, Tenofovir disoproxil fumarate is not advisable to be used during breastfeeding. In fact, women with chronic HBV infection and HIV infection is not advisable to breastfeed their babies.

Driving Generally Safe

Tenofovir disoproxil fumarate usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

Caution use and dose adjustment may be needed in patients with kidney impairment.

Liver Use With Care

Tenofovir disoproxil fumarate is safe to be used in patients with liver impairment.