Trifluoperazine

Information About Trifluoperazine

Uses of Trifluoperazine

Trifluoperazine is commonly used to treat nausea and vomiting, anxiety, anxiety disorder and schizophrenia

How Trifluoperazine Works

Trifluoperazine blocks the postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain.

Side Effects of Trifluoperazine

Drowsiness, Dry mouth, Blurred vision, Sedation, Postural hypotension, Muscle weakness, Insomnia, Abnormal muscle movements

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Trifluoperazine Related Warnings

Alcohol Not Advisable

It is not advisable to consume alcohol and Trifluoperazine concomitantly as alcohol will further depress the neurological function.

Pregnancy Not Safe

Animal studies have shown reproductive toxicities but the results are conflicting. There is no clinical evidence to show reproductive toxicities in pregnant women. Thus, Trifluoperazine is not advisable to be used during pregnancy unless necessary. Please consult your doctor.

Lactation Limited Data

Animal studies have shown secretion of Trifluoperazine in animal milk but there are limited data on human studies. Thus, Trifluoperazine is not advisable to be used during breastfeeding unless necessary. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Trifluoperazine may cause side effects such as drowsiness, dizziness or visual disturbances, all of which could affect your ability to concentrate and drive.

Kidney Use With Care

Caution use of Trifluoperazine has to be practised in patients with kidney impairment.

Liver Limited Data

Caution use of Trifluoperazine has to be practised in patients with liver impairment.