Ziprasidone

Information About Ziprasidone

Uses of Ziprasidone

Ziprasidone is commonly used to treat mania, schizophrenia

How Ziprasidone Works

Ziprasidone binds strongly to 5-HT2A/D2 receptor. It can also bind moderately to norepinephrine and serotonin reuptake sites.

Side Effects of Ziprasidone

Sleepiness, Rash, Stomach disturbances, Neurological disturbances, Weight gain, Extrapyramidal symptoms, Tardive dyskinesia, Hyperglycemia, Sexual dysfunction

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ziprasidone Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Ziprasidone. Taking Ziprasidone with alcohol may have additive effects in sleepiness and neurological disturbances.

Pregnancy Not Safe

Ziprasidone usage is not advisable during pregnancy as animal studies have shown potential risks on the foetus. It can only be used when the benefits outweigh the risks. Please consult your doctor.

Lactation Limited Data

Ziprasidone safety during breastfeeding is not well established. It can only be used when the benefits outweigh the risks. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Ziprasidone may cause side effects such as sleepiness, impairment of judgement, thinking or motor skills, all of which could affect your ability to concentrate and drive.

Kidney Use With Care

Dose adjustment is needed for patients with kidney impairment.

Liver Limited Data

Ziprasidone is safe to use in patients with liver impairment.