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Isentress 400mg Tablet

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RM 2732.10
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Introduction of Isentress 400mg Tablet

It is recommended in combination with other HIV medications. Your doctor will recommend the right medication to you to determine which dosage you require.

Before taking this medication, notify the doctor whether you have any issues with the skin or liver or kidney failure. You will require routine blood tests to verify the blood count and liver function. Stop consuming alcohol as it may escalate your risk of liver injury. Pregnant or breast-feeding mothers should contact the doctor before taking this medicine. Do not have unprotected sex or sharing personal products.


1. Flexner C. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1658-659.

2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 866-67.Briggs GG, Freeman RK, editors. 

3. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1192-194.

4. Raltegravir potassium. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2007 [revised 18 Oct. 2018]. [Accessed 28 Jan 2019] (online). Whitehouse Station, New Jersey: MERCK & CO., Inc.; 2007 [revised Jul. 2009]. [Accessed 01 Apr. 2019] (online)

5. BNF 73

6. Raltegravir (400Mg), Consumer Medication Information Leaflet, Quest3 Bpfk

Precautionary Steps of Isentress 400mg Tablet

Alcohol Warning( Not Advisable )
Alcohol can further damage the liver which is one of the side effects of Isentress 400mg Tablet. Thus, it is not advisable to consume alcohol during the treatment with Isentress 400mg Tablet.

Pregnancy Warning (Not Safe)
Animal studies have shown reproductive toxicities but human studies have not shown any reproductive toxicities. Thus, caution use of Isentress 400mg Tablet has to be practised during pregnancy. Please consult your doctor.

Breastfeeding Warning ( Not Advisable )
Excretion of Isentress 400mg Tablet is found in animal milk but not in human breast milk. An HIV-infected woman should not breastfeed to prevent HIV transmission, developing viral resistance and serious side effects onto the breastfed babies. Please consult your doctor.

Driving Warning ( Not Advisable )
Do not drive unless you are feeling well. Isentress 400mg Tablet may cause side effects such as dizziness which could affect your ability to concentrate and drive.

Kidney Warning ( Safe If Prescribed )
Isentress 400mg Tablet is safe to be used in patients with kidney impairment. Please consult your doctor.

Liver Warning ( Use With Care )
Caution use has to be practised in patients with severe liver impairment as safety and efficacy of Isentress 400mg Tablet have not been established in this group of patients. Please consult your doctor.
As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.

Many side effects do not need immediate medical attention and resolve as the body responds to the medication. Tell the doctor if they continue or if you are concerned about them.

Some of the typical side effects are anxiety (difficulty sleeping), headache, nausea, dizziness, and muscle discomfort. These are generally not harmful, just inform the doctor if they affect you or continue for a prolonged period of time. Rarely, some patients can have skin reactions or liver injury. Your doctor may observe you carefully during the initial recovery period.

Skin rash, Abdominal pain, Diarrhea, Nausea, Vomiting, Liver dysfunction, Kidney failure, Increased triglycerides and cholesterol, Hyperglycaemia, Rhabdomyolysis, Osteonecrosis, Decreased white blood cells/platelets

  • Take it with or without food, ideally every day. 
  • Do not miss any doses and finish medication even though you feel better. 
  • Do not take antacids or calcium supplements one hour or two hours before taking Isentress 400mg Tablet. 
  • Your doctor can conduct routine blood tests to control your blood cell counts and liver function throughout this medication.
  • Inform the doctor about conception, planning pregnancy or breastfeeding.

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Information last updated on: : Wed Dec 08 2021 12:24:52 GMT+0800 (Malaysia Time)

The product images shown are for illustration purposes only and may not be an exact representation of the product

The content provided on this webpage is to provide information only, to be fully-interpreted by a medical professional, and not intended as a guide to make purchase decisions, or a substitute to advice of a medical professional. Effectiveness and side effects of medication may differ from individual to individual. We do not encourage any customer to self-diagnose and/or self-medicate. Patients should always consult a medical professional before taking or using any medication. The content provided here is non-exhaustive and may not cover all aspects of the medication. Our service should only be used to support the doctor-patient dynamic, not replace it.

The fulfilment of prescription medication is subject to our review of a prescription issued by a Malaysian Medical Council (MMC) registered doctor. If required, we will provide a tele-consult service with one of our registered panel doctors. This is not an advertisement of a medicine as such an advertisement would require prior approval from the Medicines Advertisement Board of Malaysia.

Isentress 400mg Tablet is available in many areas in Malaysia. Kuala Lumpur, Bukit Bintang, Titiwangsa, Setiawangsa, Wangsa Maju, Kepong, Segambut, Bandar Tun Razak, Cheras, Subang Jaya, Petaling Jaya, Mont Kiara, Puchong, Bandar Sunway, TTDI, Seri Kembangan, Klang, Bukit Tinggi, Damansara, Sentul, Penang, George Town, Jelutong, Gelugor, Bayan Baru, Bandar Baru Air Itam, Sungai Ara, Bukit Mertajam, Butterworth, Perai, Johor Bahru, Skudai, Bukit Indah, Gelang Patah, Senai, Pasir Gudang, Taman Daya, Taman Molek, Taman Perling, Tebrau, Danga Bay, Larkin, Nusajaya, Pontian, Masai, Setia Tropika, Desaru, Tampoi.

Isentress 400mg Tablet is available at many places in Singapore. Ang Mo Kio, Alexandra, Admiralty, Bedok, Bishan, Bukit Batok, Bukit Merah, Bukit Panjang, Bukit Timah, Boat Quay, Buona Vista, Beach Road, Bugis, Balestier, Boon Lay, Central Area, Choa Chu Kang, Clementi, Chinatown, Commonwealt, City Hall, Clarke Quay, Changi Airport, Changi Village, Clementi Park, Dairy Farm, Eunos, East Coast, Farrer Park, Geylang, Hougang, Harbourfront, Holland, Jurong, Jurong East, Jurong West, Kallang/ Whampoa, Lim Chu Kang, Marine Parade, Marina, Macpherson, Mandai, Newton, Novena, Orchard, Pasir Ris, Punggol, Potong Pasir, Paya Lebar, Queenstown, Raffles Place, Rochor, River Valley, Sembawang, Sengkang, Serangoon, Serangoon Rd, Seletar, Tampines, Toa Payoh, Tanjong Pagar, Telok Blangah, Tanglin, Thomson, Tuas, Tengah, Upper East Coast, Upper Bukit Timah, Upper Thomson, Woodlands, West Coast, Yishun, Yio Chu Kang.

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