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Tretinon 0.05% Cream 20g - DoctorOnCall Online Pharmacy
Tretinon 0.05% Cream 20g - DoctorOnCall Online Pharmacy
Tretinon 0.05% Cream 20g - DoctorOnCall Online Pharmacy Tretinon 0.05% Cream 20g - DoctorOnCall Online Pharmacy

Tretinon 0.05% Cream 20g

It is advised to speak to a medical professional before consuming this product
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100% Authentic
We ensure that all our pharmaceutical products including health supplements and traditional preparations are registered with the National Pharmaceutical Regulatory Authority (NPRA) Malaysia
Free Delivery on orders above RM120
Enjoy free delivery with a minimum spend of RM120 on our platform.
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Only applicable if all items in your cart qualify for same-day delivery. Only registered users may qualify for same-day delivery, so sign up now!
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Term & Condition
100% Authentic
We ensure that all our pharmaceutical products including health supplements and traditional preparations are registered with the National Pharmaceutical Regulatory Authority (NPRA) Malaysia
Free Delivery on orders above RM120
Enjoy free delivery with a minimum spend of RM120 on our platform.
Same day Delivery
Only applicable if all items in your cart qualify for same-day delivery. Only registered users may qualify for same-day delivery, so sign up now!

Product Overview

Introduction of Tretinon 0.05% Cream 20g

Tretinoin 0.05% Cream is a topical retinoid medication containing tretinoin as its active ingredient — a derivative of Vitamin A that has been trusted in dermatology for decades. As a prescription-grade topical treatment, this cream belongs to the retinoid drug class and is widely recognised by healthcare professionals across Malaysia and globally. Like most effective skincare treatments, it does come with some things you should be aware of before starting — common side effects include skin redness, peeling, dryness, and a mild burning or stinging sensation, especially during the early weeks of use. If you are considering adding this cream to your skincare or treatment routine, it is important that you use it under proper medical guidance, follow the recommended application instructions carefully, and understand that results take time and patience — but with consistent and responsible use, many users find it to be a worthwhile part of their dermatological care plan.

How to Take Tretinoin 0.05% Cream

Tretinoin 0.05% Cream is intended for external use only and should be applied to clean, dry skin — typically in the evening or at night, as directed by your doctor or pharmacist. Use only a small, pea-sized amount and gently spread a thin layer over the affected area, avoiding sensitive zones such as the eyes, nostrils, mouth, and any broken or irritated skin. Always wash your hands thoroughly before and after application, and never apply more than the recommended amount, as overuse can increase the risk of skin irritation.

Dosage of Tretinoin 0.05% Cream

The generally recommended dosage for Tretinoin 0.05% Cream is once daily application at night, applying a thin layer to the affected area as advised by your prescribing doctor or licensed pharmacist. Dosage frequency and duration may vary depending on individual skin tolerance and the specific condition being managed, so always follow your healthcare provider's personalised instructions rather than adjusting the dose on your own.

Shelf Life of Tretinoin 0.05% Cream

Tretinoin 0.05% Cream typically has a shelf life of 2 to 3 years from the date of manufacture when stored under the correct conditions. Always check the expiry date printed on the packaging before use, and do not use the product beyond its expiry date, even if it appears unchanged in texture or colour. Once opened, it is advisable to use the cream within the period indicated on the tube or as recommended by your pharmacist.

How to Store Tretinoin 0.05% Cream

  • Store at room temperature between 15°C to 25°C
  • Keep away from direct sunlight, heat, and humidity — avoid storing in bathrooms or near windows
  • Do not freeze this product, as freezing can alter the cream's consistency and effectiveness
  • Keep the tube tightly closed when not in use
  • Store in a cool, dry place, out of reach of children and pets
  • Do not transfer the cream into another container — keep it in its original packaging
  • If you notice any changes in colour, smell, or texture, do not use the product and consult your pharmacist

Active Ingredient of Tretinoin 0.05% Cream

ComponentDetails
Active IngredientTretinoin (All-trans retinoic acid)
Concentration0.05% w/w
Drug ClassTopical Retinoid (Vitamin A Derivative)
Formulation TypeTopical Cream

Tretinoin is a naturally occurring derivative of Vitamin A and is classified as a first-generation retinoid. It is a pharmacologically active compound that has been extensively studied and documented in peer-reviewed dermatological literature, making it one of the most well-established active ingredients in topical skincare medicine.

Side Effects of Tretinoin 0.05% Cream

It is important to be aware of potential side effects before using Tretinoin 0.05% Cream. While not everyone will experience these reactions, knowing what to watch for helps you use the product safely and responsibly.

Common Side Effects:

  • Skin redness (erythema) at the application site
  • Dryness and flaking or peeling of the skin
  • Mild burning, stinging, or tingling sensation upon application
  • Increased skin sensitivity, particularly to sunlight (photosensitivity)
  • Temporary worsening of skin appearance during the initial weeks of use (purging phase)
  • Itching or mild irritation at the treated area
  • Warmth or a feeling of tightness on the skin

Less Common Side Effects:

  • Blistering or crusting of the skin
  • Swelling or oedema at the application site
  • Skin discolouration — either darkening (hyperpigmentation) or lightening (hypopigmentation)
  • Severe skin irritation or contact dermatitis
  • Unusual skin texture changes

Seek immediate medical attention if you experience:

  • Signs of an allergic reaction such as hives, difficulty breathing, or swelling of the face, lips, or throat
  • Severe blistering or open wounds on the skin
  • Extreme redness or burning that does not subside

⚠️ If any side effect persists or worsens, discontinue use and consult your doctor or pharmacist promptly.

Contraindications of Tretinoin 0.05% Cream

  • Hypersensitivity or allergy to tretinoin, any other retinoids, or any of the excipients in the formulation
  • Pregnancy — tretinoin is classified as Pregnancy Category C/D (depending on regulatory authority); topical retinoids are generally not recommended during pregnancy due to potential risks
  • Breastfeeding — use is not advised unless specifically directed by a doctor, as safety data is limited
  • Sunburned, windburned, or severely irritated skin — do not apply to compromised or broken skin
  • Active eczema, rosacea, or perioral dermatitis in the treatment area — may worsen these conditions
  • Concurrent use of other potentially irritating topical agents on the same area without medical supervision
  • Children under 12 years of age — safety and efficacy have not been well established in young children

📌 Always inform your doctor about your full medical history, current medications, and any known allergies before starting Tretinoin 0.05% Cream.

Drug & Food Interactions of Tretinoin 0.05% Cream

Drug Interactions to Be Aware Of:

  • Other topical retinoids (e.g., adapalene, tazarotene) — concurrent use may significantly increase skin irritation and should be avoided
  • Benzoyl peroxide — when used simultaneously, may cause oxidative inactivation of tretinoin and increase irritation; use at separate times if prescribed together
  • Topical antibiotics (e.g., clindamycin, erythromycin) — generally considered compatible but should be used as directed to avoid compounding irritation
  • Salicylic acid or alpha-hydroxy acid (AHA) products — combining with tretinoin may intensify skin peeling and sensitivity
  • Photosensitising medications (e.g., certain antibiotics like tetracyclines, thiazide diuretics, fluoroquinolones) — may increase the risk of sunburn or photosensitivity reactions when used alongside tretinoin
  • Medicated or abrasive skincare products containing alcohol, astringents, spices, or lime — may cause additional dryness and irritation
  • Oral Vitamin A supplements or other retinoid-based oral medications — concurrent use may lead to additive retinoid toxicity

Food & Lifestyle Interactions:

  • Sun exposure — tretinoin increases photosensitivity; prolonged or unprotected sun exposure should be minimised during treatment
  • Alcohol-based skincare or toners — may compound dryness and irritation when used on tretinoin-treated skin

💡 This is not a complete list of all possible interactions. Always consult your healthcare provider or pharmacist for personalised advice.

Quick Tips for Tretinoin 0.05% Cream

  • ✅ Always do a patch test before full application — apply a small amount to a discreet area and wait 24 hours to check for any adverse reaction
  • ✅ Apply at night only — tretinoin breaks down in sunlight and your skin is more receptive to treatment during overnight hours
  • ✅ Use a broad-spectrum sunscreen (SPF 30 or higher) every morning without fail — your skin will be more sensitive to UV rays during treatment
  • ✅ Start slow — if you are new to tretinoin, consider applying every other night initially to allow your skin to adjust
  • ✅ Less is more — a pea-sized amount is sufficient for the entire face; using more does not speed up results and only increases irritation
  • ✅ Moisturise regularly — use a gentle, fragrance-free moisturiser to help manage dryness and peeling
  • ✅ Keep the cream away from children — store in a secure location out of reach at all times
  • ✅ Check the expiry date before every use and never use expired medication
  • ✅ Do not share your prescription cream with others — what works for you may not be safe or suitable for someone else
  • ✅ Dispose of unused or expired cream responsibly — consult your pharmacist on proper medication disposal in Malaysia
  • ✅ Keep it in its original tube and packaging — do not transfer to another container as this may compromise product integrity
  • ✅ Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using this product

Frequently Asked Questions (FAQs) About Tretinoin 0.05% Cream

Q1: Can I purchase Tretinoin 0.05% Cream online in Malaysia?
 Yes, you can purchase Tretinoin 0.05% Cream through our licensed online pharmacy in Malaysia. We are committed to providing genuine, pharmacy-grade medications with a safe and straightforward ordering process — all from the comfort of your home.

Q2: Do I need a prescription to buy Tretinoin 0.05% Cream in Malaysia? 
Tretinoin is a prescription-only medication (POM) in Malaysia, regulated under the Control of Drugs and Cosmetics Regulations. You will be required to provide a valid prescription from a registered doctor when purchasing. Our platform is designed to support responsible dispensing in line with Malaysian pharmaceutical regulations.

Q3: How do I know the Tretinoin 0.05% Cream sold on your website is authentic? 
We source all our products from authorised pharmaceutical distributors and licensed suppliers registered with the Ministry of Health Malaysia (MOH). Every product listed on our platform is genuine, properly labelled, and compliant with local regulatory standards. You can also verify product authenticity by checking the manufacturer's batch number and registration details.

Q4: Is your online pharmacy licensed to operate in Malaysia?
 Yes, our online pharmacy operates in full compliance with Malaysian pharmaceutical laws and guidelines set by the Pharmacy Board Malaysia and the Ministry of Health Malaysia (MOH). We are committed to safe, ethical, and transparent dispensing practices.

Q5: How long does delivery take for Tretinoin 0.05% Cream within Malaysia?
 We offer delivery across Peninsular Malaysia, Sabah, and Sarawak. Standard delivery typically takes 3 to 5 working days, while express delivery options may be available for selected areas. Orders are carefully packaged to maintain product integrity during transit.

Q6: Will my Tretinoin 0.05% Cream be properly packaged during delivery?
 Absolutely. We take product safety seriously — all orders are packed in discreet, secure packaging to protect the product from heat, light, and physical damage during shipping. This ensures the cream reaches you in perfect condition.

Q7: Can I order Tretinoin 0.05% Cream if I live in East Malaysia (Sabah or Sarawak)? 
Yes, we deliver to both East and West Malaysia. Delivery timelines to East Malaysia may be slightly longer — typically 5 to 7 working days — but we ensure your order is handled with the same level of care and professionalism.

Q8: What payment methods are accepted for online orders in Malaysia? 
We accept a variety of convenient and secure payment options including online banking (FPX), credit and debit cards, and select e-wallet platforms commonly used in Malaysia. All transactions are processed through a secure payment gateway to protect your financial information.

Q9: What should I do if my order arrives damaged or if I receive the wrong product? 
If your order arrives damaged, tampered with, or incorrect, please contact our customer service team immediately with your order details and photos of the product. We will work promptly to resolve the issue, whether through a replacement or refund, in accordance with our returns and exchange policy.

Q10: Can I track my order after purchasing Tretinoin 0.05% Cream online?
 Yes, once your order has been dispatched, you will receive a tracking number via email or SMS so you can monitor your delivery status in real time through our courier partner's platform.

Q11: Is it safe to buy prescription medication like Tretinoin online in Malaysia?
 It is safe when purchased from a legitimate, licensed online pharmacy. We strongly advise against purchasing prescription medications from unverified or unlicensed sources, as counterfeit or substandard products pose serious health risks. Always ensure the platform you purchase from is regulated and requires a valid prescription.

Q12: How should I store Tretinoin 0.05% Cream after it is delivered to me?
 Upon receiving your order, store the cream at room temperature (15°C to 25°C), away from direct sunlight, heat, and moisture. Do not refrigerate or freeze the product. Keep it in its original packaging and out of reach of children.

Q13: Can I cancel or modify my order after it has been placed? 
Order cancellations or modifications may be possible within a limited window after the order is placed. Please contact our customer service team as soon as possible if you need to make changes. Once an order has been dispatched, cancellations may no longer be possible.

Q14: Will my personal and medical information be kept confidential when ordering online? 
Yes, we take your privacy very seriously. All personal, medical, and payment information submitted through our platform is handled in accordance with Malaysia's Personal Data Protection Act (PDPA 2010). Your data is never shared with unauthorised third parties.

Frequently Bought Together

Brands

YSP

Active Ingredient

tretinoin 

Manufactured by

Y.S.P (M) Industries Sdn Bhd

Side Effects

As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.

Fever, Skin dryness, Dryness of mouth, Irregular heartbeat, Flushing, Low blood pressure, Skin irritation, Stinging sensation, Skin pigmentation, Photosensitivity

Warning Precautions

Alcohol Warning (Not Advisable)

Using alcohol with Tretinon 0.05% Cream 20g may cause unfavourable interactions to occur whether it is used systemically or topically. Discuss with your healthcare professional the use of your medicine with alcohol.

Pregnancy Warning (Not Safe)

Though there is a limited amount of data from the use of Tretinon 0.05% Cream 20g in pregnant women but there is a high risk of severe malformation of the fetus, particularly if given during the first trimester, therefore, it must not be used during pregnancy, especially during the first trimester unless the condition of the mother requires treatment with Tretinon 0.05% Cream 20g.

Breastfeeding Warning (Not Advisable)

It is excreted into the breast milk. Discontinue breastfeeding once Tretinon 0.05% Cream 20g therapy is initiated

Driving Warning (Not Advisable)

Do not drive unless you are feeling well. Tretinon 0.05% Cream 20g may cause side effects such as dizziness, headches, nausea or palpitations, all of which could affect the ability to concentrate and drive.

Kidney Warning (Use With Care)

Tretinon 0.05% Cream 20g should use with caution in a patient with impaired kidney functions. A renal profile may be done before starting Tretinon 0.05% Cream 20g therapy and the first month after initiating it.

Liver Warning (Use With Care)

Tell your doctor if you have any liver diseases since it is metabolized in the liver. Your doctor might have to adjust the dose accordingly. Monitoring is also needed as it can cause liver toxicity.

FAQ

Disclaimer

Information last updated on: Thu Apr 09 2026 03:30:20 GMT+0000 (Coordinated Universal Time) The product images shown are for illustration purposes only and may not be an exact representation of the product.

The content provided on this webpage is to provide information only, to be fully-interpreted by a medical professional, and not intended as a guide to make purchase decisions, or a substitute to advice of a medical professional. Effectiveness and side effects of medication may differ from individual to individual. We do not encourage any customer to self-diagnose and/or self-medicate. Patients should always consult a medical professional before taking or using any medication. The content provided here is non-exhaustive and may not cover all aspects of the medication. Our service should only be used to support the doctor-patient dynamic, not replace it.

The fulfilment of prescription medication is subject to our review of a prescription issued by a Malaysian Medical Council (MMC) registered doctor. If required, we will provide a tele-consult service with one of our registered panel doctors. This is not an advertisement of a medicine as such an advertisement would require prior approval from the Medicines Advertisement Board of Malaysia. Tretinon 0.05% Cream 20g is available in many areas in Malaysia. Kuala Lumpur, Bukit Bintang, Titiwangsa, Setiawangsa, Wangsa Maju, Kepong, Segambut, Bandar Tun Razak, Cheras, Subang Jaya, Petaling Jaya, Mont Kiara, Puchong, Bandar Sunway, TTDI, Seri Kembangan, Klang, Bukit Tinggi, Damansara, Sentul, Penang, George Town, Jelutong, Gelugor, Bayan Baru, Bandar Baru Air Itam, Sungai Ara, Bukit Mertajam, Butterworth, Perai, Johor Bahru, Skudai, Bukit Indah, Gelang Patah, Senai, Pasir Gudang, Taman Daya, Taman Molek, Taman Perling, Tebrau, Danga Bay, Larkin, Nusajaya, Pontian, Masai, Setia Tropika, Desaru, Tampoi.


Tretinon 0.05% Cream 20g is available at many places in Singapore. Ang Mo Kio, Alexandra, Admiralty, Bedok, Bishan, Bukit Batok, Bukit Merah, Bukit Panjang, Bukit Timah, Boat Quay, Buona Vista, Beach Road, Bugis, Balestier, Boon Lay, Central Area, Choa Chu Kang, Clementi, Chinatown, Commonwealt, City Hall, Clarke Quay, Changi Airport, Changi Village, Clementi Park, Dairy Farm, Eunos, East Coast, Farrer Park, Geylang, Hougang, Harbourfront, Holland, Jurong, Jurong East, Jurong West, Kallang/ Whampoa, Lim Chu Kang, Marine Parade, Marina, Macpherson, Mandai, Newton, Novena, Orchard, Pasir Ris, Punggol, Potong Pasir, Paya Lebar, Queenstown, Raffles Place, Rochor, River Valley, Sembawang, Sengkang, Serangoon, Serangoon Rd, Seletar, Tampines, Toa Payoh, Tanjong Pagar, Telok Blangah, Tanglin, Thomson, Tuas, Tengah, Upper East Coast, Upper Bukit Timah, Upper Thomson, Woodlands, West Coast, Yishun, Yio Chu Kang.
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