Ciprofibrate

Information About Ciprofibrate

Uses of Ciprofibrate

Ciprofibrate is commonly used to treat high cholesterol

How Ciprofibrate Works

Ciprofibrate acts on the nuclear transcription factor PPAR-alpha which upregulates the apolipoprotein A-1 gene and downregulate the apolipoprotein C-11 gene.

Side Effects of Ciprofibrate

Rashes, Itchiness, Muscle weakness, Vertigo, Headache, Nausea, Vomiting, Dizziness, Somnolence, Light sensitivity

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ciprofibrate Related Warnings

Alcohol Not Advisable

Ciprofibrate and alcohol consumption may worsen the effects on the central nervous system as their adverse reactions may be compounded.

Pregnancy Not Safe - High Risk

Animal reproductive studies suggest teratogenicity and severe adverse reaction while there are no adequate human pregnant studies to suggest otherwise. It is, therefore, not advisable to be used in pregnant women without specialist recommendation.

Lactation Not Advisable

Ciprofibrate is not known to be excreted into human breastmilk and is therefore contraindicated to be used during breastfeeding.

Driving Not advisable

It is not advisable to drive when taking Ciprofibrate due to its potential side effects such as headache and dizziness which can affect the ability to drive and concentrate.

Kidney High Risk

Dosage adjustment is needed in patients with mild to moderate renal impairment and is contraindicated to be used in patients with severe renal impairment.

Liver Use With Care

Dosage adjustment is needed in patient with mild to moderate hepatic impairment while it is contraindicated to be used in severe hepatic impaired patients.