Mantle Cell Lymphoma

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University

Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Mantle Cell Lymphoma

Mantle Cell Lymphoma is an aggressive, rare form of the non-Hodgkin’s Lymphoma. It arises from the mantle zone of the lymph node and affects the B cells. The abnormal B cells accumulates in the lymph nodes and other organs and forms the tumour.

Signs and Symptoms of Mantle Cell Lymphoma

Painless superficial lymph nodes, Pruritus, Fever, Night sweats, Weight loss, Hepatosplenomegaly, Chest pain, Coughing

Common Causes of Mantle Cell Lymphoma

Genetic mutation

Risk Factors of Mantle Cell Lymphoma

Age, Gender, Family history of lymphoma, Previous Epstein-Barr infection, Exposure to certain chemicals and drugs, Radiation exposure, Autoimmune disease

Investigation Techniques for Mantle Cell Lymphoma

Full blood count, Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), Blood urea and serum electrolytes, Serum LDH, B2-microglobulin, Serum uric acid, Liver function test (LFT), Chest X-ray, CT scan, PET scan, Bone marrow aspirate, Lymph node biopsy