Axcel Clindamycin 1% Topical Solution

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Overview

Axcel Clindamycin 1% Topical Solution is a topical antibiotic preparation containing Clindamycin Phosphate 1%, formulated as a liquid solution for direct application to the skin. Clindamycin is a lincosamide-class antibiotic that works against the bacteria implicated in inflammatory acne, and the topical solution format allows the medicine to be applied precisely to affected areas of the face, back, or chest without the need for oral antibiotics.

This product is used in the management of mild to moderately severe acne vulgaris, particularly inflammatory lesions such as papules and pustules. Because it is an antibiotic-based prescription treatment, Axcel Clindamycin 1% Topical Solution is classified as a prescription (Rx) medicine in Malaysia, and it should only be used under the guidance of a doctor or pharmacist following an online consultation through DoctorOnCall, so that suitability, dosing, and duration of use are properly assessed.

How it Works

Clindamycin Phosphate is converted to active clindamycin on the skin, where it works by binding to bacterial ribosomes and inhibiting protein synthesis in Cutibacterium acnes (formerly Propionibacterium acnes), the bacteria strongly associated with inflammatory acne. By reducing the bacterial population on the skin surface and within follicles, it helps decrease inflammation, redness, and the formation of new papules and pustules over time.

Directions for Use

Wash and gently pat dry the affected area before use. Apply a thin, even layer of the solution to the affected skin using the applicator or a clean cotton pad, avoiding the eyes, lips, mouth, and other mucous membranes. Allow the solution to dry before applying any other topical products, and wash hands thoroughly after application. Use only as directed by your doctor or pharmacist.

Dosage

The typical dosing is application once or twice daily to the affected areas, as advised by the prescribing doctor. Treatment duration is usually assessed after several weeks, as visible improvement in acne can take 4 to 8 weeks of consistent use. Do not increase the frequency or amount applied in an attempt to speed up results, as this raises the risk of skin irritation without improving efficacy.

Shelf Life

Axcel Clindamycin 1% Topical Solution should be used within the shelf-life period printed on the bottle and carton when stored correctly. Do not use the product beyond its expiry date, and check the solution for any change in colour, consistency, or odour before each use.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly closed when not in use and out of reach of children. Do not store in the bathroom cabinet if humidity and temperature fluctuate significantly there.

Side Effects

Clindamycin Topical

  • Skin dryness
  • Itching or a slight burning sensation
  • Skin peeling or redness
  • Oily skin
  • Irritation at the application site

Clindamycin

  • Nausea or vomiting
  • Diarrhoea
  • Abdominal pain
  • Rash or itching
  • Metallic taste in the mouth
  • In rare cases, severe intestinal condition (Clostridium difficile infection)

Contraindications

  • Known hypersensitivity to clindamycin, lincomycin, or any ingredient in the solution
  • History of antibiotic-associated colitis (e.g., pseudomembranous colitis) linked to clindamycin or lincomycin
  • Not for use on open wounds, eczema, or broken skin unless directed by a doctor
  • Not recommended for children without medical supervision

Drug / Food Interactions

  • Avoid concurrent use with other topical acne products (e.g., benzoyl peroxide, retinoids) unless advised by a doctor, as combined use may increase skin irritation
  • Caution with other topical antibiotics to reduce the risk of bacterial resistance
  • Erythromycin-containing topical products should not be used together with clindamycin due to antagonistic effects
  • Inform your doctor of all other skincare or medicated products in use before starting treatment

Quick Tips

  • Apply to clean, dry skin for best absorption
  • Use sun protection during the day as treated skin may be more sensitive
  • Do not apply near the eyes, mouth, or mucous membranes
  • Complete the full course as advised by your doctor, even if improvement is seen early
  • Report any severe irritation, diarrhoea, or signs of allergic reaction to your doctor promptly
  • Follow up with your prescribing doctor via DoctorOnCall if acne does not improve within the expected timeframe

Frequently Asked Questions

What is Axcel Clindamycin 1% Topical Solution used for?

It is a prescription topical antibiotic solution containing Clindamycin Phosphate 1%, used to treat inflammatory acne such as papules and pustules by reducing acne-causing bacteria on the skin.

How do I apply Axcel Clindamycin 1% Topical Solution correctly?

Apply a thin layer to clean, dry, affected skin once or twice daily as directed by your doctor, avoiding the eyes, mouth, and mucous membranes.

What side effects can occur with Axcel Clindamycin 1% Topical Solution?

Common side effects include dryness, peeling, mild burning, or irritation at the application site; severe reactions such as allergic rash or diarrhoea should be reported to a doctor immediately.

Who should not use Axcel Clindamycin 1% Topical Solution?

Individuals with a known allergy to clindamycin or lincomycin, or a history of antibiotic-associated colitis, should not use this product without medical clearance.

How long does it take to see results with Axcel Clindamycin 1% Topical Solution?

Visible improvement in acne typically takes about 4 to 8 weeks of consistent, correct use as prescribed by a doctor.

Can I purchase Axcel Clindamycin 1% Topical Solution through DoctorOnCall in Malaysia or Singapore?

Yes, Axcel Clindamycin 1% Topical Solution is available through DoctorOnCall, a licensed online pharmacy serving Malaysia and Singapore. As this is a prescription medicine, an online consultation is required so a doctor can assess your suitability and issue a prescription before the order is processed.

Is Axcel Clindamycin 1% Topical Solution supplied by DoctorOnCall genuine and safe to use for customers in Malaysia and Singapore?

Yes, all stock is sourced through licensed pharmacy supply channels and dispensed and checked by a registered pharmacist before it reaches customers in Malaysia and Singapore.

What payment methods can I use to pay for Axcel Clindamycin 1% Topical Solution in Malaysia and Singapore?

You can pay using Online Banking, Credit Card, and e-Wallets (Boost, GrabPay), among other available options at checkout.

Does DoctorOnCall offer an installment payment plan for Axcel Clindamycin 1% Topical Solution in Malaysia?

An installment payment plan is available for eligible purchases where applicable; please contact Customer Service for the latest information.

Is delivery free, and how much does it cost for Axcel Clindamycin 1% Topical Solution orders to Malaysia and Singapore?

Delivery fees depend on the delivery location and order terms; please contact Customer Service for the latest fee information.

How long will it take for my Axcel Clindamycin 1% Topical Solution order to arrive in Malaysia or Singapore?

Orders typically take 3-5 working days to arrive within Malaysia and 5-9 working days for delivery to Singapore.

What is DoctorOnCall’s shipping, return, or cancellation policy for Axcel Clindamycin 1% Topical Solution in Malaysia and Singapore?

Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service for detailed guidance.

Ingredients / Active Ingredients

  • Clindamycin Phosphate equivalent to 1% Clindamycin

Safety Advice

Clindamycin Topical

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Generally Safe

Generally safe, but caution may be required in some patients.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Clindamycin

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

As a prescription topical antibiotic, Axcel Clindamycin 1% Topical Solution is best used as part of a broader acne management plan that may include gentle cleansing, non-comedogenic moisturisers, and sun protection. A doctor’s assessment via DoctorOnCall helps confirm this is the right treatment for your skin type and acne severity before dispensing.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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Important Medical Information

💊 Recommended Dosage:

The typical dosing is application once or twice daily to the affected areas, as advised by the prescribing doctor. Treatment duration is usually assessed after several weeks, as visible improvement in acne can take 4 to 8 weeks of consistent use. Do not increase the frequency or amount applied in an attempt to speed up results, as this raises the risk of skin irritation without improving efficacy.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to clindamycin, lincomycin, or any ingredient in the solution
  • History of antibiotic-associated colitis (e.g., pseudomembranous colitis) linked to clindamycin or lincomycin
  • Not for use on open wounds, eczema, or broken skin unless directed by a doctor
  • Not recommended for children without medical supervision
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Clindamycin Topical:
  • Skin dryness
  • Itching or a slight burning sensation
  • Skin peeling or redness
  • Oily skin
  • Irritation at the application site
Clindamycin:
  • Nausea or vomiting
  • Diarrhoea
  • Abdominal pain
  • Rash or itching
  • Metallic taste in the mouth
  • In rare cases, severe intestinal condition (Clostridium difficile infection)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.