Daflon 1000mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Daflon 1000mg Tablet is a film-coated tablet made by Servier, supplied in Malaysia through Servier Malaysia Sdn Bhd. Each tablet contains 1000 mg of micronised purified flavonoid fraction (MPFF), made up of Diosmin 900 mg and flavonoids expressed as Hesperidin 100 mg. The micronised form is a refined preparation of plant-derived flavonoids and is presented as a single-ingredient tablet.

Daflon is also sold as a 500 mg tablet (Diosmin 450 mg and Hesperidin 50 mg), so the strength on the pack should always be checked against the dose that has been advised for you. Daflon 1000mg is supplied in packs of 10 or 30 tablets, and the pack size you receive depends on the product listing you choose. It is a medicine and not a food supplement.

Daflon 1000mg is supplied through pharmacies. The rules on how it may be supplied can differ from country to country, so please confirm with a pharmacist or doctor whether it is suitable for you and how it should be taken before you order. The product information advises that treatment should be avoided during pregnancy and lactation, and it should not be used by anyone allergic to any of its ingredients.

Directions for Use

  • Swallow the tablet whole with a glass of water, preferably with a meal.
  • Follow the regimen that your doctor or pharmacist has advised, or the directions printed on the pack insert.
  • The standard regimen is one tablet (1000 mg) once daily with a meal, preferably in the morning.
  • A short higher-dose regimen, when advised by a doctor or pharmacist, is up to 3 tablets daily in divided doses for the first 4 days, followed by 2 tablets daily in divided doses for the next 3 days.
  • Do not exceed 3 tablets (3000 mg) in 24 hours.
  • Do not use after the expiry date printed on the pack.

Dosage

Standard regimen: one Daflon 1000mg tablet (1000 mg) once daily, taken with a meal. Short higher-dose regimen, when advised by a doctor or pharmacist: up to 3 tablets a day in 3 divided doses for the first 4 days, then 2 tablets a day in 2 divided doses for the next 3 days. Do not exceed 3000 mg (3 tablets) in 24 hours. If a dose is missed, take the next dose with the next meal as normal; do not take a double dose. If symptoms do not settle promptly, or if they return, do not keep self-treating; please see a doctor for assessment.

Storage Instructions

Store as directed on the pack, in a cool, dry place away from direct sunlight and moisture, and keep the tablets in their original strip until use. Keep out of the reach and sight of children.

Side Effects

  • Mild gastrointestinal upset (nausea, indigestion)
  • Headache
  • Dizziness
  • Skin rash or itching (rare)

Contraindications

  • Do not use in anyone with a known allergy or hypersensitivity to diosmin, hesperidin or flavonoids, or to any of the other ingredients in the tablet.
  • Treatment should be avoided during pregnancy and breastfeeding according to the product information; speak to a doctor before use.

Drug / Food Interactions

  • No clinically significant drug interactions are described in the Malaysian product information reviewed, but please tell your doctor or pharmacist about all prescription, OTC and herbal products you take.
  • No specific food interactions are described; the tablet is usually taken with a meal.
  • Do not take other products containing diosmin, hesperidin or other flavonoid fractions at the same time unless a doctor or pharmacist has advised it, to avoid doubling the dose.

Quick Tips

  • Check the strength on the pack: this is the 1000 mg tablet (900 mg diosmin and 100 mg hesperidin), not the 500 mg tablet.
  • Take the tablet with a meal and swallow it whole with water.
  • Keep a note of the days and number of tablets taken if you are following a short higher-dose regimen.
  • Tell your doctor or pharmacist if you are pregnant, planning a pregnancy or breastfeeding before taking it.
  • Keep the tablets in their original strip and carton, and away from damp, heat and children.
  • Keep your doctor informed if symptoms do not settle promptly, even while taking the tablets.

Ingredients / Active Ingredients

  • Active ingredient: Micronised purified flavonoid fraction (MPFF) 1000 mg per film-coated tablet.
  • Composition of the fraction: Diosmin 900 mg and flavonoids expressed as Hesperidin 100 mg.
  • Dosage form: film-coated tablet; packs of 10 or 30 tablets.
  • Excipients (including the tablet coating) are not listed in the sources reviewed; please refer to the pack insert for the complete list.

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Safe If Prescribed

Use during breastfeeding should only be done if prescribed and monitored by a doctor.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Not Advisable

Not recommended in patients with liver disease.

Alcohol

Generally Safe

Consuming alcohol with this medicine is generally safe, but moderate intake is advised.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Precautions: Daflon 1000mg should be avoided during pregnancy and breastfeeding according to the product information, so please speak to a doctor first if either applies to you. Do not use it if you are allergic to any of its ingredients. Follow the regimen advised by your doctor or pharmacist and do not exceed 3 tablets in 24 hours. The product has a negligible effect on driving and the use of machines, but if you feel dizzy, avoid driving until you feel well.

When to See a Doctor or Pharmacist: See a doctor or pharmacist if your symptoms do not settle promptly, return after treatment, or are accompanied by bleeding, severe or persistent pain, or fever. Stop taking the tablets and seek urgent medical help if you develop swelling of the face, lips, tongue or throat, difficulty breathing, a widespread rash, or persistent severe diarrhoea or abdominal pain.

Frequently Asked Questions

Product Specifications

BrandZuellig Pharma
ClassificationNon-prescription
Ingredients / Active IngredientsDiosmin + Hesperidin
Pack Size10s, 30s
Shelf LifeUse before the expiry date printed on the strip and outer carton. Do not use tablets that are past their expiry date or whose strip packaging is damaged.

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