Imdur 60mg Tablet

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Manufacturer AstraZeneca
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Imdur 60mg Tablet is a prescription-only medicine (POM) that contains Isosorbide mononitrate 60mg (extended-release). It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Imdur 60mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Imdur 60mg Tablet once daily in the morning, with or without food. Swallow the extended-release tablet whole with water; do not crush, chew, or break it, as this can release the medicine too quickly. This medicine is for preventing angina and is not intended to relieve chest pain that is already occurring.

Dosage

The usual dose of Imdur 60mg Tablet is one tablet once daily in the morning, as extended-release isosorbide mononitrate is designed to provide a nitrate-free interval later in the day to reduce the risk of the body becoming tolerant to the medicine. Your doctor will individualise the dose based on your angina symptoms and response to treatment.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Dizziness or light-headedness
  • Low blood pressure
  • Flushing (warmth or redness in the face)
  • Fatigue
  • Nausea

Contraindications

  • Known hypersensitivity to isosorbide mononitrate or other nitrates
  • Concomitant use with PDE5 inhibitors (e.g. sildenafil, tadalafil, vardenafil) or riociguat, due to the risk of severe, potentially life-threatening low blood pressure
  • Severe anaemia
  • Acute circulatory failure or cardiogenic shock
  • Conditions with raised intracranial pressure, such as recent head trauma or cerebral haemorrhage

Drug / Food Interactions

  • PDE5 inhibitors (sildenafil, tadalafil, vardenafil) and riociguat – must not be combined, as this can cause severe, life-threatening low blood pressure
  • Alcohol may increase dizziness and the blood-pressure-lowering effect
  • Other blood pressure medicines or vasodilators may increase the risk of low blood pressure
  • Sapropterin and other nitric-oxide-donating agents may add to the vasodilator effect

Quick Tips

  • Take at the same time each morning to preserve the built-in nitrate-free interval
  • Rise slowly from sitting or lying down to reduce dizziness
  • Tell every doctor or pharmacist you see that you take this medicine before starting any new treatment, especially for erectile dysfunction
  • Do not stop this medicine abruptly without medical advice, as this can worsen angina

Ingredients / Active Ingredients

  • Isosorbide mononitrate 60mg (extended-release)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandAstraZeneca
ManufacturerAstraZeneca
ClassificationPrescription medicine
Ingredients / Active IngredientsIsosorbide Mononitrate
Pack Size105s, 15s, 30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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