Pharmaniaga Gliclazide 80mg Tablet

Pharmaniaga Gliclazide 80mg Tablet contains gliclazide, a second-generation sulfonylurea medicine used in the management of type 2 diabetes mellitus in adults, alongside diet and exercise, when blood glucose is not adequately controlled by lifestyle measures alone. It works by stimulating the pancreas to release more insulin, helping to lower blood glucose levels and reduce the risk of long-term diabetes-related complications.

As a sulfonylurea antidiabetic medicine, Pharmaniaga Gliclazide 80mg Tablet is a prescription-only product in Malaysia. It is supplied through DoctorOnCall only after an online consultation, during which a doctor reviews your diabetes history, current blood glucose control, and other medicines before determining an appropriate starting dose and monitoring plan.

Gliclazide binds to sulfonylurea receptors on the beta cells of the pancreas, causing closure of ATP-sensitive potassium channels. This leads to calcium influx into the beta cells and triggers the release of stored insulin into the bloodstream, which in turn helps cells throughout the body take up glucose more effectively, lowering blood glucose levels in people with type 2 diabetes.

Take Pharmaniaga Gliclazide 80mg Tablet exactly as prescribed by your doctor, typically with breakfast or the first main meal of the day, to help reduce the risk of low blood sugar (hypoglycaemia). Do not skip meals after taking this medicine, and do not change your dose without first consulting your doctor.

The dose of Pharmaniaga Gliclazide 80mg Tablet is individualised by the prescribing doctor based on blood glucose monitoring, typically starting at a low dose such as 40 to 80mg daily and adjusted gradually, up to a maximum daily dose as advised, which may be taken as a single dose or in divided doses with meals. Regular blood glucose and HbA1c monitoring is used to guide dose adjustments.

Pharmaniaga Gliclazide 80mg Tablet typically has a shelf life of around 36 months from the date of manufacture when stored unopened under the recommended conditions. Always check the expiry date printed on the blister strip and outer carton before use.

Store Pharmaniaga Gliclazide 80mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture. Keep in the original packaging until ready for use, and out of the reach and sight of children.

• Type 1 diabetes mellitus or diabetic ketoacidosis
• Severe kidney or liver impairment
• Known hypersensitivity to gliclazide, other sulfonylureas, or sulfonamide-derived medicines
• Pregnancy and breastfeeding, where alternative diabetes treatments are generally preferred

• Alcohol can increase the risk and unpredictability of hypoglycaemia when combined with gliclazide
• Other antidiabetic medicines, including insulin, may increase the overall blood-glucose-lowering effect and hypoglycaemia risk when combined
• Certain antibiotics (such as sulfonamides) and some antifungal medicines may enhance the glucose-lowering effect
• NSAIDs and some other medicines that are highly protein-bound may increase gliclazide’s effect
• Corticosteroids and thiazide diuretics can reduce blood glucose control and may require dose review
• Beta-blockers may mask some of the warning symptoms of hypoglycaemia, such as a fast heartbeat

• Take with breakfast or your first main meal to reduce the risk of low blood sugar
• Learn to recognise the symptoms of hypoglycaemia (shakiness, sweating, confusion, hunger) and how to treat it promptly
• Do not skip meals after taking your dose
• Monitor your blood glucose regularly as advised by your doctor
• Attend scheduled follow-up appointments and blood tests, including HbA1c monitoring

Pharmaniaga Gliclazide 80mg Tablet requires ongoing medical supervision because the dose needs to be matched to each patient’s blood glucose response, and because sulfonylureas carry a real risk of hypoglycaemia if the dose, meal timing, or other medicines are not managed carefully. This is why an online consultation with a doctor via DoctorOnCall is required before this medicine is dispensed, and why regular follow-up is an important part of treatment.