Nasodren 50mg/5ml Nasal Spray
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Overview
Nasodren 50mg/5ml Nasal Spray is a nasal spray containing a purified extract of Cyclamen europaeum (sowbread) tuber in purified water, supplied in a bottle providing around 38 doses. Unlike a plain saline rinse or spray, Nasodren is formulated with a specific botanical active ingredient that acts through a local reflex mechanism in the nasal mucosa, distinct from simple saline irrigation.
It is an over-the-counter nasal spray intended for short courses only, following the package insert and pharmacist guidance, rather than for everyday nasal hygiene. Because its active ingredient works differently from ordinary saline, it should be used strictly according to the package insert and pharmacist guidance rather than assumed to behave like a saline spray.
How it Works
The active ingredient, Cyclamen europaeum tuber extract, acts on local nerve receptors in the nasal mucosa when sprayed into the nostril, triggering a reflex response that produces a brief, marked increase in mucus and fluid secretion within the nose and paranasal sinuses. This temporary surge in secretion is accompanied by loosening of mucus and debris in the nasal passages, which then passes out through the nose along with the secretion. This mechanism is distinct from isotonic saline products, which work by simple mechanical rinsing rather than triggering a secretory reflex.
Directions for Use
Before first use, prime the pump as instructed on the packaging. With the head upright (not tilted back or lying down), insert the nozzle into one nostril and spray once, then repeat in the other nostril. Remain upright for a short period afterwards rather than lying down immediately, to allow the expected increase in nasal and sinus secretion to drain naturally. Blow your nose gently as needed afterwards. Clean the nozzle tip after use according to the package instructions.
Dosage
The typical adult dose is one spray into each nostril, generally once daily, as directed on the product packaging or by a doctor or pharmacist. Do not increase the frequency or number of sprays beyond what is directed, as the reflex secretory effect is intended to be used in a controlled, short course rather than repeated multiple times a day.
Shelf Life
Do not use beyond the expiry date printed on the packaging. Once the bottle is opened, use within the timeframe stated on the package insert, as the number of usable doses in an opened bottle may reduce over time.
Storage Instructions
Store at room temperature, away from direct sunlight, heat, and moisture, and keep the bottle upright with the cap closed between uses, following the specific storage conditions printed on the packaging. Keep out of reach of children.
Side Effects
- Common: Temporary stinging or burning sensation in the nose after spraying.
- Common: Sneezing and watery eyes shortly after use.
- Common: A marked, temporary increase in nasal and sinus discharge, which is an expected part of how the product works.
- Serious: Frequent, heavy, or prolonged nosebleeds, significant facial or ear pain, or signs of an allergic reaction such as swelling or difficulty breathing, which require prompt medical attention.
Contraindications
- Do not use if you have a known hypersensitivity to Cyclamen europaeum, other plants in the Primulaceae family, or any other ingredient in the product.
- Do not use during pregnancy or while breastfeeding unless specifically advised by a doctor or pharmacist.
- Do not use in children unless specifically advised by a doctor or pharmacist, as this product’s use in paediatric patients should be guided by professional advice rather than self-directed use.
Drug / Food Interactions
- Avoid using other nasal decongestants, medicated nasal sprays, or nasal corticosteroids at the same time without checking with a doctor or pharmacist, as combined use on the nasal mucosa may increase irritation or affect how each product works.
- Inform your doctor or pharmacist of any other sinus or allergy medicines you are taking before starting Nasodren.
- No specific food interactions are documented for this product.
Quick Tips
- Use Nasodren while standing or sitting upright, not lying down, so secretions can drain naturally.
- Expect a short burst of sneezing, watery eyes, and increased nasal discharge after each dose — this is generally expected, not a sign of a problem.
- Do not exceed the dose or duration stated on the packaging or by your pharmacist.
- Keep tissues on hand after each use to manage the temporary increase in discharge.
- Do not share your Nasodren bottle with other people.
- See a doctor if you feel you need to use Nasodren for longer than the recommended course, rather than continuing to self-treat indefinitely.
Frequently Asked Questions
What makes Nasodren different from an ordinary saline nasal spray?
Nasodren is not a plain saline product. It contains a purified extract of Cyclamen europaeum (sowbread) tuber, a botanical active ingredient that works through a local reflex mechanism rather than simply moistening the nose. Because of this, its dosing, expected effects, and precautions are different from saline sprays or rinses.
Why do I sneeze and have watery eyes and increased nasal discharge after using Nasodren?
These reactions are an expected part of how Nasodren works. The extract stimulates local nasal nerve endings and briefly increases mucus and fluid secretion, which is part of the product’s reflex action. This increased discharge is generally considered a sign the product is acting, but should settle down within a short time after each dose.
How many doses are in one bottle of Nasodren, and how long does a course typically last?
Each bottle of Nasodren provides around 38 doses. Follow the course duration and frequency stated in the package insert or as advised by your doctor or pharmacist, and do not extend a course beyond what is directed without professional advice.
Can I use Nasodren if I am pregnant, breastfeeding, or considering it for a child?
Because Nasodren contains a botanical extract with a specific pharmacological action rather than plain saline, it should not be used during pregnancy or breastfeeding, or given to children, unless a doctor or pharmacist has specifically advised it after reviewing the package insert. Always check with a healthcare professional first in these situations.
Can I use Nasodren together with other nasal sprays or sinus medicines?
Tell your doctor or pharmacist about any other nasal products, decongestants, or sinus medicines you are using before starting Nasodren, as combining products acting on the nasal mucosa may increase irritation or alter how each product works. Do not combine products without professional advice.
Is it normal to have a mild nosebleed after using Nasodren?
A mild, occasional nosebleed can occur given the reflex secretory effect of the extract, but frequent, heavy, or prolonged bleeding is not expected and should be reported to a doctor or pharmacist promptly.
Can I purchase Nasodren 50mg/5ml Nasal Spray online through DoctorOnCall in Malaysia or Singapore?
Yes, Nasodren 50mg/5ml Nasal Spray is available for purchase through DoctorOnCall as an online pharmacy serving customers in Malaysia and Singapore. As with any over-the-counter product, please read the product label and follow the recommended directions, and speak with our pharmacist team if you have any questions before ordering.
Is the product supplied by DoctorOnCall genuine and safe to use?
Products supplied through DoctorOnCall are sourced and handled through the appropriate pharmacy supply process. As with any product, please use Nasodren 50mg/5ml Nasal Spray according to the product instructions and professional advice, and contact our pharmacist team if you have any concerns about your order.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay), so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Nasodren 50mg/5ml Nasal Spray?
DoctorOnCall provides an installment payment plan for eligible purchases where applicable. Available plans, eligibility, and terms can vary, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does it cost?
Delivery charges may depend on your delivery location and the applicable order and delivery terms. For the latest delivery fee information for Malaysia or Singapore, please contact DoctorOnCall Customer Service.
How long will it take for my order to arrive?
Orders to Malaysia are generally delivered within 3-5 working days, and orders to Singapore are generally delivered within 5-9 working days, although actual delivery time may vary depending on the delivery location, order processing, courier operations, weekends, and public holidays.
What is DoctorOnCall’s shipping, return, or cancellation policy for Nasodren 50mg/5ml Nasal Spray?
Shipping, return, and cancellation terms may vary depending on the product, your order details, and whether you are ordering from Malaysia or Singapore. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Extract of Cyclamen europaeum tuber (main active ingredient)
- Purified water
Related Health Conditions
Relevant Information
Precautions: Nasodren contains an active botanical extract that produces a reflex secretory effect, so it should be used strictly as directed rather than as a routine daily nasal hygiene product. It is not recommended during pregnancy or breastfeeding, or for children, without professional advice, and should be used cautiously by anyone with a history of nasal or sinus surgery, nosebleeds, or known sensitivity to plants in the Primulaceae family.
When to See a Doctor or Pharmacist: Speak with a doctor or pharmacist before starting Nasodren if you are pregnant, breastfeeding, considering use in a child, or taking other nasal or sinus medicines, and seek prompt medical attention if you develop heavy or prolonged nosebleeds, severe facial pain, high fever, or any signs of an allergic reaction. Also see a doctor if you feel you need to use Nasodren for longer than the recommended course.
Medical Review
Reviewed by:
Doctor of Medicine (MD), University of Mansoura - Manchester

