Herbs Of Gold L-Citrulline+L-Arginine Capsule

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Herbs Of Gold L-Citrulline+L-Arginine Capsule is an amino acid dietary supplement from Herbs of Gold, an Australian supplement brand. Each capsule combines two amino acids, L-citrulline and L-arginine, and according to the product information provides 300mg of each per capsule. The product is supplied as oral capsules in a bottle of 60 capsules; please refer to the product label to confirm the exact pack size and full ingredient list.

L-arginine is a conditionally essential amino acid: the body makes some of it, and it is also obtained from protein-rich foods such as meat, poultry, fish, dairy, nuts and legumes. It is used in protein synthesis, in the urea cycle that helps the body handle nitrogen, and in the production of several signalling molecules and creatine. L-citrulline is a non-protein amino acid found naturally in watermelon, and the kidneys convert it into L-arginine, which is why the two are often paired in one formula.

This combination may be used as a dietary supplement by adults who wish to add these amino acids to their daily intake, for example alongside an active lifestyle. It is not a substitute for a balanced diet or for any treatment prescribed by your doctor. Because both amino acids can lower blood pressure and interact with certain heart medicines, adults who take nitrates, PDE5 inhibitors such as sildenafil or tadalafil, or blood pressure medicines should speak to a doctor or pharmacist before use.

Directions for Use

Swallow the capsules whole with a glass of water. The product information suggests taking it on an empty stomach, or about 30 to 60 minutes before physical activity. Take it at around the same time each day and always follow the directions printed on the product label or the advice of your doctor or pharmacist.

Dosage

Adults: the product information indicates 2 to 4 capsules daily, or as advised by a healthcare professional. Please confirm the recommended dose on the product label before use, as label directions take priority.

Do not exceed the recommended daily intake. This product is not intended for children or adolescents. If you miss a dose, simply take the next dose at the usual time; do not double up.

Storage Instructions

Store in a cool, dry place, away from direct sunlight, heat and moisture. Keep the container tightly closed after each use and keep it out of reach of children. Follow any additional storage instructions printed on the product label.

Side Effects

  • Common: stomach discomfort, bloating, nausea or abdominal cramps, which are more likely at higher intakes.
  • Common: diarrhoea or loose stools, especially when the product is taken in larger amounts.
  • Common: mild headache, a tingling sensation or flushing, which is usually short-lived.
  • Less common: dizziness or light-headedness related to a drop in blood pressure, particularly when combined with blood pressure medicines.
  • Serious: allergic reactions such as rash, itching, swelling of the face, lips or throat, or difficulty breathing; worsening of asthma symptoms has also been reported with L-arginine. Stop use and seek urgent medical attention.

Contraindications

  • People who have had a recent heart attack: L-arginine is not recommended after a heart attack, as a clinical study in this group raised safety concerns.
  • People taking nitrates for angina or chest pain, unless specifically approved by their doctor.
  • People with low blood pressure, or those prone to dizziness or fainting.
  • People with a history of herpes infections (including cold sores), as L-arginine may support herpes virus activity in laboratory studies.
  • People with known allergy or hypersensitivity to L-arginine, L-citrulline or any other ingredient in the product.
  • People with guanidinoacetate methyltransferase (GAMT) deficiency, an inherited disorder of creatine metabolism.

Drug / Food Interactions

  • Nitrates (e.g. glyceryl trinitrate, isosorbide mononitrate or dinitrate, used for angina): L-arginine and L-citrulline may add to the blood-pressure-lowering effect of nitrates and increase the risk of dizziness or fainting. Do not combine without your doctor’s advice.
  • PDE5 inhibitors (e.g. sildenafil, tadalafil): taking these amino acids together with a PDE5 inhibitor may cause an additive drop in blood pressure. Speak to your doctor or pharmacist before combining them.
  • Blood pressure medicines (e.g. ACE inhibitors, angiotensin receptor blockers, calcium channel blockers, beta blockers, diuretics): there may be an additive blood-pressure-lowering effect, so your blood pressure may need closer monitoring.
  • ACE inhibitors, angiotensin receptor blockers and potassium-sparing diuretics (e.g. spironolactone): L-arginine may raise blood potassium levels, particularly in people with reduced kidney function.
  • Diabetes medicines: L-arginine may influence blood sugar levels, so people taking glucose-lowering medicines should monitor their readings and speak to their doctor.
  • Other L-arginine or L-citrulline products (including pre-workout powders and amino acid blends): taking several together increases your total intake and the likelihood of stomach upset and blood pressure effects.

Quick Tips

  • Check the label of any pre-workout or sports drink you use, as many already contain L-arginine or L-citrulline.
  • Start at the lower end of the label dose to see how your stomach tolerates it.
  • If you feel dizzy or light-headed after taking it, sit or lie down and speak to your pharmacist before continuing.
  • Tell your doctor you take this supplement before starting any new heart, blood pressure or PDE5 inhibitor medicine.
  • Keep the bottle tightly closed and stored away from bathroom humidity.
  • Continue to get protein from a varied, balanced diet; the supplement is an addition, not a replacement.

Ingredients / Active Ingredients

  • L-Citrulline: 300mg per capsule
  • L-Arginine: 300mg per capsule
  • Key ingredients: L-citrulline 300mg and L-arginine 300mg per capsule, according to the product information.
  • Serving information: 1 capsule; the product information indicates 2 to 4 capsules daily for adults. Refer to the label for the confirmed serving size.
  • Dosage form: oral capsule.
  • Other ingredients: please refer to the product label for the capsule shell material and any excipients.

Relevant Information

Precautions: This product is intended for adults. There is not enough reliable information on the safety of supplemental L-arginine or L-citrulline during pregnancy or breastfeeding, so do not use it during these times unless your doctor advises it. Use with caution if you have kidney disease, liver disease, diabetes, asthma or allergies, or if you are taking any blood pressure, heart or diabetes medicines. Stop taking the product at least two weeks before planned surgery, as it may affect blood pressure. Avoid taking several products containing L-arginine or L-citrulline at the same time.

When to See a Doctor or Pharmacist: Speak to a doctor or pharmacist before use if you have heart disease, a history of heart attack, low or high blood pressure, kidney problems or recurrent herpes infections, or if you take nitrates, PDE5 inhibitors such as sildenafil or tadalafil, or blood pressure medicines. Stop using the product and seek medical attention promptly if you develop chest pain, fainting, severe dizziness, a rash, swelling of the face or lips, or difficulty breathing.

Frequently Asked Questions

Product Specifications

BrandHerbs Of Gold
ClassificationNon-prescription
Pack Size60s
Shelf LifeRefer to the expiry date printed on the product packaging. Do not use the capsules after the expiry date has passed.

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