Oziclide MR 60mg Tablet

Oziclide MR 60mg Tablet contains Gliclazide in a modified-release (MR) formulation of 60mg, a second-generation sulfonylurea used to help control blood glucose levels in adults with type 2 diabetes mellitus. The modified-release formulation allows the active ingredient to be released gradually over the day, enabling convenient once-daily dosing alongside diet and regular physical activity.

Oziclide MR 60mg Tablet is a prescription-only medicine in Malaysia. A valid prescription is required, and it should only be used after an online consultation with a registered doctor through DoctorOnCall, who will assess your suitability, kidney and liver function, and appropriate dosing before treatment begins.

Gliclazide works by stimulating the beta cells of the pancreas to release more insulin and by improving the sensitivity of peripheral tissues to insulin, which together help lower blood glucose levels. The modified-release matrix in Oziclide MR gradually releases the drug over approximately 24 hours, providing steady glucose control with a single daily dose rather than requiring multiple doses through the day.

Take Oziclide MR 60mg Tablet exactly as prescribed by your doctor, usually once daily with breakfast, at approximately the same time each day. Swallow the tablet whole with a glass of water; do not crush, break, or chew it, as this can disrupt the modified-release mechanism and alter how the medicine is absorbed.

The usual starting dose is one 30mg to 60mg tablet once daily, which your doctor may adjust based on your blood glucose response, up to a maximum recommended daily dose as advised by your doctor. Never adjust your dose without consulting your doctor, and attend regular blood sugar monitoring appointments.

Oziclide MR 60mg Tablet is typically stable for up to 36 months from the date of manufacture when stored correctly and unopened. Always check the expiry date printed on the packaging before use.

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep the tablets in their original packaging until ready for use, and keep out of reach of children.

• Known hypersensitivity to gliclazide, other sulfonylureas, or sulfonamides
• Type 1 diabetes mellitus
• Diabetic ketoacidosis
• Severe renal or hepatic impairment
• Pregnancy and breastfeeding (unless directed by a doctor)

• Alcohol — may increase the risk and severity of hypoglycemia
• Other glucose-lowering medicines or insulin — increased hypoglycemia risk when combined
• Beta-blockers — may mask the warning signs of hypoglycemia
• NSAIDs and certain antifungal medicines — may increase gliclazide’s blood-glucose-lowering effect
• Corticosteroids — may reduce gliclazide’s effectiveness and raise blood glucose

• Take Oziclide MR 60mg Tablet once daily with breakfast at the same time each day for consistent blood sugar control
• Swallow the tablet whole; do not crush or chew it
• Monitor your blood glucose regularly as advised by your doctor
• Carry a fast-acting source of sugar in case of hypoglycemia symptoms
• Attend scheduled follow-ups to monitor kidney, liver, and blood sugar control

The modified-release formulation of Oziclide MR provides more even blood glucose control across the day compared with immediate-release gliclazide and allows for simpler once-daily dosing, which can improve adherence to treatment. Regular monitoring of blood glucose (including HbA1c), as well as periodic assessment of kidney and liver function, is important to ensure safe and effective long-term use. Elderly patients and those with irregular meal patterns are at higher risk of hypoglycemia and should be monitored closely by their doctor.