Cosyrel 5/10mg Tablet
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Prescription Required
Overview
Cosyrel 5/10mg Tablet contains Bisoprolol 5mg and Perindopril arginine 10mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.
Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.
DoctorOnCall is a licensed online pharmacy. Orders for Cosyrel 5/10mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.
Directions for Use
Take Cosyrel 5/10mg Tablet once daily in the morning, before breakfast. Swallow the tablet whole with a glass of water. Do not stop taking this medicine suddenly without consulting your doctor – stopping a beta-blocker abruptly can trigger a rebound increase in heart rate, blood pressure, or chest pain, so any dose changes must be made gradually under medical supervision.
Dosage
Cosyrel 5/10mg Tablet is usually taken as one tablet once daily in the morning. It is intended for patients who are already stable on the individual components at matching doses; your doctor will confirm the appropriate strength for you. Always take this medicine exactly as prescribed.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or lightheadedness
- Cough
- Headache
- Tiredness or fatigue
- Nausea
- Low blood pressure
- Rash or skin irritation
- Elevated potassium levels
- Changes in kidney function
Contraindications
- Known hypersensitivity to bisoprolol, perindopril, or any other beta-blocker or ACE inhibitor
- Severe bradycardia, second- or third-degree heart block (without a pacemaker), or decompensated heart failure
- Severe asthma or severe chronic obstructive pulmonary disease (COPD)
- Previous history of angioedema related to ACE inhibitor use
- Pregnancy and breastfeeding
Drug / Food Interactions
- Other heart-rate-lowering medicines (e.g. verapamil, diltiazem) may cause severe bradycardia or heart block when combined with bisoprolol
- Potassium supplements or potassium-sparing diuretics may increase the risk of high blood potassium
- Bisoprolol can mask the warning signs of low blood sugar (such as a fast heartbeat) in patients with diabetes taking insulin or other diabetes medicines
- NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
Quick Tips
- Take at the same time each morning, before breakfast, to build a consistent routine
- Never stop this medicine abruptly – any changes must be made gradually under your doctor’s guidance
- Check your pulse periodically if advised by your doctor, and report a very slow or irregular heartbeat
- Inform your doctor if you have diabetes, as this medicine can mask signs of low blood sugar
Frequently Asked Questions
Is Cosyrel 5/10mg Tablet a prescription medicine?
Yes. Cosyrel 5/10mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
What does Cosyrel 5/10mg Tablet contain?
Cosyrel 5/10mg Tablet is supplied as a tablet and contains Bisoprolol 5mg and Perindopril arginine 10mg. The full composition is listed in the Composition section on this page and on the product packaging.
Why is there no information here about what Cosyrel 5/10mg Tablet is for?
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
How should I take Cosyrel 5/10mg Tablet?
Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.
What should I do if I miss a dose?
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
How should I store Cosyrel 5/10mg Tablet?
Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects?
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Can I stop taking Cosyrel 5/10mg Tablet on my own?
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
How do I get a prescription for Cosyrel 5/10mg Tablet?
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Cosyrel 5/10mg Tablet be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Cosyrel 5/10mg Tablet registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Bisoprolol 5mg
- Perindopril arginine 10mg
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
Medical Review
