Cafergot Tablet

Cafergot Tablet contains Ergotamine tartrate and Caffeine and is presented as a tablet. It is supplied in a pack size of 20s.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Cafergot Tablet should only be used according to the exact instructions provided by the prescribing doctor following an online consultation with DoctorOnCall. It is typically taken at the very first warning signs of a migraine attack, as delaying treatment can reduce its effectiveness; tablets are usually swallowed whole with water and should not be exceeded beyond the maximum dose per attack or per week set by the doctor, since ergotamine carries a risk of serious toxicity (ergotism) if overused.

The dosing regimen for Cafergot Tablet, including the initial dose, any additional doses during a single attack, and the maximum allowed per week, must be individually determined and confirmed by the prescribing doctor, since ergotamine has a narrow margin between an effective dose and a toxic one. Patients must strictly follow the maximum limits given, as taking Cafergot too frequently or in excessive amounts significantly increases the risk of severe vascular side effects.

Cafergot Tablet is generally stable for up to 24 to 36 months from the date of manufacture when stored correctly and left in its original, unopened packaging; the exact expiry date is printed on the blister strip or carton. The tablets should never be used past their expiry date, and any unused stock from a previous prescription should be checked with a pharmacist before further use.

Store Cafergot Tablet at room temperature, below 30 degrees Celsius, in a dry place away from direct sunlight, heat, and moisture. Keep the tablets in their original blister packaging until ready to use, and store out of reach and sight of children, as ergotamine can be particularly dangerous if accidentally ingested by a child.

• Known hypersensitivity or allergy to ergotamine, caffeine, or any other ergot alkaloid
• Coronary artery disease, angina, or history of heart attack
• Uncontrolled high blood pressure
• Peripheral vascular disease or conditions causing reduced blood flow to the limbs
• Severe liver or kidney impairment
• Pregnancy and breastfeeding, as ergotamine can cause serious harm to the foetus and passes into breast milk
• Sepsis or severe infection
• Use of certain medicines that strongly interact with ergotamine, such as some antifungal and antibiotic medicines, unless specifically reviewed by a doctor

• Certain antibiotics and antifungal medicines (such as macrolide antibiotics or azole antifungals) can significantly increase ergotamine blood levels and the risk of severe vasoconstriction and ergotism
• Other migraine medicines from the triptan class should not be used within 24 hours of Cafergot due to the combined risk of excessive vasoconstriction
• Beta-blockers and other vasoconstrictive medicines may increase the risk of reduced blood flow to the extremities when combined with ergotamine
• Additional caffeine from coffee, tea, or energy drinks can add to the stimulant side effects of the caffeine component
• Grapefruit juice may affect the metabolism of ergotamine and should generally be avoided unless a doctor advises otherwise
• Always inform the prescribing doctor of all other medicines and supplements being taken before starting Cafergot Tablet

• Complete the DoctorOnCall online consultation so the doctor can confirm Cafergot Tablet is safe and appropriate for your migraine pattern and cardiovascular health
• Take the tablet as early as possible at the first sign of a migraine attack for the best effect
• Never exceed the maximum dose per attack or per week set by your doctor, as overuse significantly raises the risk of serious side effects
• Seek urgent medical attention if you experience chest pain, numbness, severe limb pain, or cold, discoloured fingers or toes
• Avoid combining Cafergot with other migraine medicines, certain antibiotics, or antifungal treatments unless your doctor has confirmed it is safe

Cafergot Tablet is reserved for acute migraine treatment under close medical supervision because of ergotamine’s significant vascular effects and its potential for serious toxicity if overused or combined with certain interacting medicines. Regular follow-up with the prescribing doctor is important, particularly for patients who experience frequent migraine attacks, since overuse of ergotamine-containing medicines can itself lead to medication-overuse headache and other complications. Customers in Malaysia and Singapore can access this medicine through DoctorOnCall only after an online consultation confirms it is medically appropriate.